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Receive this page by email each issue: [Sign up for eTOCs] Other Issues: September 1 2008; 112 (5)   [Index by Author]  [Cover Caption]  [Complete Inside Blood PDF]         INSIDE BLOOD        BLOOD WORK        ASH 50TH ANNIVERSARY REVIEW        PLENARY PAPERS        REVIEW ARTICLES        CHEMOKINES, CYTOKINES, AND INTERLEUKINS        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS AND STEM CELLS        HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY        IMMUNOBIOLOGY        NEOPLASIA        PHAGOCYTES        RED CELLS        TRANSFUSION MEDICINE        TRANSPLANTATION        CORRESPONDENCE        ERRATUM Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: VEGF-D: a modifier of embryonic lymphangiogenesis Terhi Karpanen and Kari Alitalo Blood 2008 112: 1547-1548. [Full Text] [PDF]   Shear tango: dance of the ADAMTS13/VWF complex Rens de Groot and David A. Lane Blood 2008 112: 1548-1549. [Full Text] [PDF]   Where does von Willebrand factor go? Gary E. Gilbert Blood 2008 112: 1549-1550. [Full Text] [PDF]   Genomic complexity in chronic lymphocytic leukemia Thomas J. Kipps Blood 2008 112: 1550. [Full Text] [PDF]   Complement dances with T cells M. Javeed Ansari and Mohamed H. Sayegh Blood 2008 112: 1551-1552. [Full Text] [PDF]   Diamond-Blackfan anemia: a new facet Akiko Shimamura Blood 2008 112: 1552-1553. [Full Text] [PDF]   GASing up iron delivery via STAT5 Jeffrey S. Friedman Blood 2008 112: 1553-1554. [Full Text] [PDF]   Blood group antigens reveal their maker James J. Bieker Blood 2008 112: 1554-1555. [Full Text] [PDF]   BLOOD WORK: Target cells and hemoglobinopathy Blood 2008 112: 1581. [Full Text] [PDF]   ASH 50TH ANNIVERSARY REVIEW: CD4 T cells: fates, functions, and faults Jinfang Zhu and William E. Paul Blood 2008 112: 1557-1569. [Abstract] [Full Text] [PDF]   B lymphocytes: how they develop and function Tucker W. LeBien and Thomas F. Tedder Blood 2008 112: 1570-1580. [Abstract] [Full Text] [PDF]   PLENARY PAPERS: Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia Jason E. Farrar, Michelle Nater, Emi Caywood, Michael A. McDevitt, Jeanne Kowalski, Clifford M. Takemoto, C. Conover Talbot, Jr, Paul Meltzer, Diane Esposito, Alan H. Beggs, Hal E. Schneider, Agnieszka Grabowska, Sarah E. Ball, Edyta Niewiadomska, Colin A. Sieff, Adrianna Vlachos, Eva Atsidaftos, Steven R. Ellis, Jeffrey M. Lipton, Hanna T. Gazda, and Robert J. Arceci Blood 2008 112: 1582-1592. Prepublished online June 5, 2008; DOI 10.1182/blood-2008-02-140012 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   REVIEW ARTICLES: Bortezomib-induced peripheral neuropathy in multiple myeloma: a comprehensive review of the literature Andreas A. Argyriou, Gregoris Iconomou, and Haralabos P. Kalofonos Blood 2008 112: 1593-1599. Prepublished online June 23, 2008; DOI 10.1182/blood-2008-04-149385 [Abstract] [Full Text] [PDF]   European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas Nancy J. Senff, Evert M. Noordijk, Youn H. Kim, Martine Bagot, Emilio Berti, Lorenzo Cerroni, Reinhard Dummer, Madeleine Duvic, Richard T. Hoppe, Nicola Pimpinelli, Steven T. Rosen, Maarten H. Vermeer, Sean Whittaker, and Rein Willemze Blood 2008 112: 1600-1609. Prepublished online June 20, 2008; DOI 10.1182/blood-2008-04-152850 [Abstract] [Full Text] [PDF]   CHEMOKINES, CYTOKINES, AND INTERLEUKINS: CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factor Hedwich F. Kuipers, Paula J. Biesta, Lisette J. Montagne, Elise S. van Haastert, Paul van der Valk, and Peter J. van den Elsen Blood 2008 112: 1610-1619. Prepublished online May 29, 2008; DOI 10.1182/blood-2008-01-135111 [Abstract] [Full Text] [PDF]   Increased serum levels of the chemokine CXCL13 and up-regulation of its gene expression are distinctive features of HCV-related cryoglobulinemia and correlate with active cutaneous vasculitis Domenico Sansonno, Felicia Anna Tucci, Laura Troiani, Gianfranco Lauletta, Michele Montrone, Vincenza Conteduca, Loredana Sansonno, and Franco Dammacco Blood 2008 112: 1620-1627. Prepublished online June 12, 2008; DOI 10.1182/blood-2008-02-137455 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: The natural history and treatment outcome of blast phase BCR-ABL– myeloproliferative neoplasms Constantine S. Tam, Roberto M. Nussenzveig, Uday Popat, Carlos E. Bueso-Ramos, Deborah A. Thomas, Jorge A. Cortes, Richard E. Champlin, Stefan E. Ciurea, Taghi Manshouri, Sherry M. Pierce, Hagop M. Kantarjian, and Srdan Verstovsek Blood 2008 112: 1628-1637. Prepublished online June 19, 2008; DOI 10.1182/blood-2008-02-138230 [Abstract] [Full Text] [PDF]   A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome Stefan Faderl, Farhad Ravandi, Xuelin Huang, Guillermo Garcia-Manero, Alessandra Ferrajoli, Zeev Estrov, Gautam Borthakur, Srdan Verstovsek, Deborah A. Thomas, Monica Kwari, and Hagop M. Kantarjian Blood 2008 112: 1638-1645. Prepublished online June 18, 2008; DOI 10.1182/blood-2007-11-124602 [Abstract] [Full Text] [PDF]   What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies Wendy Stock, Mei La, Ben Sanford, Clara D. Bloomfield, James W. Vardiman, Paul Gaynon, Richard A. Larson, and James Nachman Blood 2008 112: 1646-1654. Prepublished online May 23, 2008; DOI 10.1182/blood-2008-01-130237 [Abstract] [Full Text] [PDF]   Brief report  Successful treatment of progressive cutaneous mastocytosis with imatinib in a 2-year-old boy carrying a somatic KIT mutation Karl M. Hoffmann, Andrea Moser, Peter Lohse, Andreas Winkler, Barbara Binder, Petra Sovinz, Herwig Lackner, Wolfgang Schwinger, Martin Benesch, and Christian Urban Blood 2008 112: 1655-1657. Prepublished online June 20, 2008; DOI 10.1182/blood-2008-03-147785 [Abstract] [Full Text] [PDF]   Brief report  CNS Hodgkin lymphoma Elizabeth R Gerstner, Lauren E Abrey, David Schiff, Andrés J. M Ferreri, Andrew Lister, Silvia Montoto, Richard Tsang, Eckhard Thiel, Francesc Graus, Dirk Behringer, Gerald Illerhaus, Susan Weaver, Patrick Wen, Alfredo Voloschin, Nancy Lee Harris, and Tracy T Batchelor Blood 2008 112: 1658-1661. Prepublished online June 30, 2008; DOI 10.1182/blood-2008-04-151563 [Abstract] [Full Text] [PDF]   GENE THERAPY: Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice Baowei Peng, Peiqing Ye, Bruce R. Blazar, Gordon J. Freeman, David J. Rawlings, Hans D. Ochs, and Carol H. Miao Blood 2008 112: 1662-1672. Prepublished online June 23, 2008; DOI 10.1182/blood-2008-01-128413 [Abstract] [Full Text] [PDF]   HEMATOPOIESIS AND STEM CELLS: Stem cell–specific epigenetic priming and B cell–specific transcriptional activation at the mouse Cd19 locus Korden Walter, Constanze Bonifer, and Hiromi Tagoh Blood 2008 112: 1673-1682. Prepublished online June 13, 2008; DOI 10.1182/blood-2008-02-142786 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A Xiaoling Zhang, Xun Shang, Fukun Guo, Kim Murphy, Michelle Kirby, Patrick Kelly, Lilith Reeves, Franklin O. Smith, David A. Williams, Yi Zheng, and Qishen Pang Blood 2008 112: 1683-1686. Prepublished online June 18, 2008; DOI 10.1182/blood-2008-03-147090 [Abstract] [Full Text] [PDF] [Supplemental Figures]   HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY: Hydroxychloroquine directly reduces the binding of antiphospholipid antibody–β2-glycoprotein I complexes to phospholipid bilayers Jacob H. Rand, Xiao-Xuan Wu, Anthony S. Quinn, Pojen P. Chen, James J. Hathcock, and Douglas J. Taatjes Blood 2008 112: 1687-1695. Prepublished online June 24, 2008; DOI 10.1182/blood-2008-03-144204 [Abstract] [Full Text] [PDF]   CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin IIbβ3 in platelets Stephen M. Cifuni, Denisa D. Wagner, and Wolfgang Bergmeier Blood 2008 112: 1696-1703. Prepublished online June 10, 2008; DOI 10.1182/blood-2008-02-139733 [Abstract] [Full Text] [PDF]   Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo Carina J. van Schooten, Shirin Shahbazi, Evelyn Groot, Beatrijs D. Oortwijn, H. Marijke van den Berg, Cécile V. Denis, and Peter J. Lenting Blood 2008 112: 1704-1712. Prepublished online June 16, 2008; DOI 10.1182/blood-2008-01-133181 [Abstract] [Full Text] [PDF]   Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity Weiqiang Gao, Patricia J. Anderson, and J. Evan Sadler Blood 2008 112: 1713-1719. Prepublished online May 20, 2008; DOI 10.1182/blood-2008-04-148759 [Abstract] [Full Text] [PDF]   Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos Alexandre Trindade, S. Ram Kumar, Jeffrey S. Scehnet, Luis Lopes-da-Costa, Jorg Becker, Weidong Jiang, Ren Liu, Parkash S. Gill, and Antonio Duarte Blood 2008 112: 1720-1729. Prepublished online June 17, 2008; DOI 10.1182/blood-2007-09-112748 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis Youya Nakazawa, Shigeo Sato, Mikihiko Naito, Yukinari Kato, Kazuhiko Mishima, Hiroyuki Arai, Takashi Tsuruo, and Naoya Fujita Blood 2008 112: 1730-1739. Prepublished online June 9, 2008; DOI 10.1182/blood-2007-11-124693 [Abstract] [Full Text] [PDF]   Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles Annelii Ny, Marta Koch, Wouter Vandevelde, Martin Schneider, Christian Fischer, Antonio Diez-Juan, Elke Neven, Ilse Geudens, Sunit Maity, Lieve Moons, Stéphane Plaisance, Diether Lambrechts, Peter Carmeliet, and Mieke Dewerchin Blood 2008 112: 1740-1749. Prepublished online May 12, 2008; DOI 10.1182/blood-2007-08-106302 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   IMMUNOBIOLOGY: Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists James L. Wynn, Philip O. Scumpia, Robert D. Winfield, Matthew J. Delano, Kindra Kelly-Scumpia, Tolga Barker, Ricardo Ungaro, Ofer Levy, and Lyle L. Moldawer Blood 2008 112: 1750-1758. Prepublished online June 30, 2008; DOI 10.1182/blood-2008-01-130500 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Locally produced C5a binds to T cell–expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis Peter N. Lalli, Michael G. Strainic, Min Yang, Feng Lin, M. Edward Medof, and Peter S. Heeger Blood 2008 112: 1759-1766. Prepublished online June 20, 2008; DOI 10.1182/blood-2008-04-151068 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development Fukun Guo, Jose A. Cancelas, David Hildeman, David A. Williams, and Yi Zheng Blood 2008 112: 1767-1775. Prepublished online June 25, 2008; DOI 10.1182/blood-2008-01-132068 [Abstract] [Full Text] [PDF]   Human natural killer cells exposed to IL-2, IL-12, IL-18, or IL-4 differently modulate priming of naive T cells by monocyte-derived dendritic cells Sophie Agaugué, Emanuela Marcenaro, Bruna Ferranti, Lorenzo Moretta, and Alessandro Moretta Blood 2008 112: 1776-1783. Prepublished online June 25, 2008; DOI 10.1182/blood-2008-02-135871 [Abstract] [Full Text] [PDF] [Supplemental Figure]   STAT3 is required for IL-21–induced secretion of IgE from human naive B cells Danielle T. Avery, Cindy S. Ma, Vanessa L. Bryant, Brigitte Santner-Nanan, Ralph Nanan, Melanie Wong, David A. Fulcher, Matthew C. Cook, and Stuart G. Tangye Blood 2008 112: 1784-1793. Prepublished online June 25, 2008; DOI 10.1182/blood-2008-02-142745 [Abstract] [Full Text] [PDF] [Supplemental Figures]   The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-B through its N-terminal fragment Jae Jin Chae, Geryl Wood, Katharina Richard, Howard Jaffe, Nona T. Colburn, Seth L. Masters, Deborah L. Gumucio, Nitza G. Shoham, and Daniel L. Kastner Blood 2008 112: 1794-1803. Prepublished online June 24, 2008; DOI 10.1182/blood-2008-01-134932 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression Heike Schmidlin, Sean A. Diehl, Maho Nagasawa, Ferenc A. Scheeren, Remko Schotte, Christel H. Uittenbogaart, Hergen Spits, and Bianca Blom Blood 2008 112: 1804-1812. Prepublished online June 13, 2008; DOI 10.1182/blood-2008-01-136440 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells Jeremy B. Samon, Ameya Champhekar, Lisa M. Minter, Janice C. Telfer, Lucio Miele, Abdul Fauq, Pritam Das, Todd E. Golde, and Barbara A. Osborne Blood 2008 112: 1813-1821. Prepublished online June 11, 2008; DOI 10.1182/blood-2008-03-144980 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Adenosine receptors in regulation of dendritic cell differentiation and function Sergey V. Novitskiy, Sergey Ryzhov, Rinat Zaynagetdinov, Anna E. Goldstein, Yuhui Huang, Oleg Y. Tikhomirov, Michael R. Blackburn, Italo Biaggioni, David P. Carbone, Igor Feoktistov, and Mikhail M. Dikov Blood 2008 112: 1822-1831. Prepublished online June 17, 2008; DOI 10.1182/blood-2008-02-136325 [Abstract] [Full Text] [PDF]   STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells Peter A. Cohen, Gary K. Koski, Brian J. Czerniecki, Kevin D. Bunting, Xin-Yuan Fu, Zhengqi Wang, Wen-Jun Zhang, Charles S. Carter, Mohamed Awad, Christopher A. Distel, Hassan Nagem, Christopher C. Paustian, Terrence D. Johnson, John F. Tisdale, and Suyu Shu Blood 2008 112: 1832-1843. Prepublished online June 24, 2008; DOI 10.1182/blood-2007-12-130138 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Targeting a single mismatched minor histocompatibility antigen with tumor-restricted expression eradicates human solid tumors Lothar Hambach, Marcel Vermeij, Andreas Buser, Zohara Aghai, Theodorus van der Kwast, and Els Goulmy Blood 2008 112: 1844-1852. Prepublished online June 10, 2008; DOI 10.1182/blood-2007-11-125492 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   β2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding Heikki Takala, Elisa Nurminen, Susanna M. Nurmi, Maria Aatonen, Tomas Strandin, Maarit Takatalo, Tiila Kiema, Carl G. Gahmberg, Jari Ylänne, and Susanna C. Fagerholm Blood 2008 112: 1853-1862. Prepublished online June 12, 2008; DOI 10.1182/blood-2007-12-127795 [Abstract] [Full Text] [PDF]   A novel polymorphism of the human CD40 receptor with enhanced function Anna L. Peters, Robert M. Plenge, Robert R. Graham, David M. Altshuler, Kathy L. Moser, Patrick M. Gaffney, and Gail A. Bishop Blood 2008 112: 1863-1871. Prepublished online June 30, 2008; DOI 10.1182/blood-2008-02-138925 [Abstract] [Full Text] [PDF]   Brief report  Detection of T lymphocytes with a second-site mutation in skin lesions of atypical X-linked severe combined immunodeficiency mimicking Omenn syndrome Taizo Wada, Masahiro Yasui, Tomoko Toma, Yuko Nakayama, Mika Nishida, Masaki Shimizu, Michiko Okajima, Yoshihito Kasahara, Shoichi Koizumi, Masami Inoue, Keisei Kawa, and Akihiro Yachie Blood 2008 112: 1872-1875. Prepublished online June 16, 2008; DOI 10.1182/blood-2008-04-149708 [Abstract] [Full Text] [PDF]   NEOPLASIA: Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia Concetta Quintarelli, Gianpietro Dotti, Biagio De Angelis, Valentina Hoyos, Martha Mims, Luigia Luciano, Helen E. Heslop, Cliona M. Rooney, Fabrizio Pane, and Barbara Savoldo Blood 2008 112: 1876-1885. Prepublished online June 30, 2008; DOI 10.1182/blood-2008-04-150045 [Abstract] [Full Text] [PDF] [Supplemental Figures]   HDAC6 inhibition enhances 17-AAG–mediated abrogation of hsp90 chaperone function in human leukemia cells Rekha Rao, Warren Fiskus, Yonghua Yang, Pearl Lee, Rajeshree Joshi, Pravina Fernandez, Aditya Mandawat, Peter Atadja, James E. Bradner, and Kapil Bhalla Blood 2008 112: 1886-1893. Prepublished online June 30, 2008; DOI 10.1182/blood-2008-03-143644 [Abstract] [Full Text] [PDF]   Analysis of clonotypic switch junctions reveals multiple myeloma originates from a single class switch event with ongoing mutation in the isotype-switched progeny Brian J. Taylor, Jitra Kriangkum, Julie A. Pittman, Michael J. Mant, Tony Reiman, Andrew R. Belch, and Linda M. Pilarski Blood 2008 112: 1894-1903. Prepublished online June 24, 2008; DOI 10.1182/blood-2008-01-129221 [Abstract] [Full Text] [PDF]   Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth Marta Segarra, Cassin Kimmel Williams, Maria de la Luz Sierra, Marcelino Bernardo, Peter J. McCormick, Dragan Maric, Celeste Regino, Peter Choyke, and Giovanna Tosato Blood 2008 112: 1904-1911. Prepublished online June 24, 2008; DOI 10.1182/blood-2007-11-126045 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism Dunyaporn Trachootham, Hui Zhang, Wan Zhang, Li Feng, Min Du, Yan Zhou, Zhao Chen, Helene Pelicano, William Plunkett, William G. Wierda, Michael J. Keating, and Peng Huang Blood 2008 112: 1912-1922. Prepublished online June 23, 2008; DOI 10.1182/blood-2008-04-149815 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia Laura Z. Rassenti, Sonia Jain, Michael J. Keating, William G. Wierda, Michael R. Grever, John C. Byrd, Neil E. Kay, Jennifer R. Brown, John G. Gribben, Donna S. Neuberg, Feng He, Andrew W. Greaves, Kanti R. Rai, and Thomas J. Kipps Blood 2008 112: 1923-1930. Prepublished online June 24, 2008; DOI 10.1182/blood-2007-05-092882 [Abstract] [Full Text] [PDF] [Supplemental Table]   Biologic and genetic characterization of the novel amyloidogenic lambda light chain–secreting human cell lines, ALMC-1 and ALMC-2 Bonnie K. Arendt, Marina Ramirez-Alvarado, Laura A. Sikkink, Jonathan J. Keats, Gregory J. Ahmann, Angela Dispenzieri, Rafael Fonseca, Rhett P. Ketterling, Ryan A. Knudson, Erin M. Mulvihill, Renee C. Tschumper, Xiaosheng Wu, Steven R. Zeldenrust, and Diane F. Jelinek Blood 2008 112: 1931-1941. Prepublished online June 20, 2008; DOI 10.1182/blood-2008-03-143040 [Abstract] [Full Text] [PDF] [Supplemental Table]   Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBP in p210BCR/ABL-expressing cells Angela Rachele Soliera, Maria Rosa Lidonnici, Giovanna Ferrari-Amorotti, Marco Prisco, Ying Zhang, Robert V. Martinez, Nick J. Donato, and Bruno Calabretta Blood 2008 112: 1942-1950. Prepublished online June 12, 2008; DOI 10.1182/blood-2007-09-114975 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Sµ mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells Philippe Ruminy, Fabrice Jardin, Jean-Michel Picquenot, Françoise Parmentier, Nathalie Contentin, Gérard Buchonnet, Sandrine Tison, Vinciane Rainville, Hervé Tilly, and Christian Bastard Blood 2008 112: 1951-1959. Prepublished online May 30, 2008; DOI 10.1182/blood-2007-11-124560 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Absence of SKP2 expression attenuates BCR-ABL–induced myeloproliferative disease Anupriya Agarwal, Thomas G. P. Bumm, Amie S. Corbin, Thomas O'Hare, Marc Loriaux, Jonathan VanDyke, Stephanie G. Willis, Jutta Deininger, Keiichi I. Nakayama, Brian J. Druker, and Michael W. Deininger Blood 2008 112: 1960-1970. Prepublished online June 17, 2008; DOI 10.1182/blood-2007-09-113860 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells Kumudha Balakrishnan, William G. Wierda, Michael J. Keating, and Varsha Gandhi Blood 2008 112: 1971-1980. Prepublished online June 19, 2008; DOI 10.1182/blood-2007-12-126946 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells Winnie F. Tam, Ting-Lei Gu, Jing Chen, Benjamin H. Lee, Lars Bullinger, Stefan Fröhling, Andrew Wang, Stefano Monti, Todd R. Golub, and D. Gary Gilliland Blood 2008 112: 1981-1992. Prepublished online June 17, 2008; DOI 10.1182/blood-2007-07-103010 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia Lisa Kujawski, Peter Ouillette, Harry Erba, Chris Saddler, Andrzej Jakubowiak, Mark Kaminski, Kerby Shedden, and Sami N. Malek Blood 2008 112: 1993-2003. Prepublished online April 24, 2008; DOI 10.1182/blood-2007-07-099432 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Primary cystic lung light chain deposition disease: a clinicopathologic entity derived from unmutated B cells with a stereotyped IGHV4-34/IGKV1 receptor Magali Colombat, Hervé Mal, Christiane Copie-Bergman, Jacques Diebold, Diane Damotte, Patrice Callard, Michel Fournier, Jean-Pierre Farcet, Marc Stern, and Marie-Hélène Delfau-Larue Blood 2008 112: 2004-2012. Prepublished online May 15, 2008; DOI 10.1182/blood-2007-11-123596 [Abstract] [Full Text] [PDF]   Brief report  DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication Susan P. Whitman, Björn Hackanson, Sandya Liyanarachchi, Shujun Liu, Laura J. Rush, Kati Maharry, Dean Margeson, Ramana Davuluri, Jing Wen, Tatiana Witte, Li Yu, Chunhui Liu, Clara D. Bloomfield, Guido Marcucci, Christoph Plass, and Michael A. Caligiuri Blood 2008 112: 2013-2016. Prepublished online June 19, 2008; DOI 10.1182/blood-2008-01-128595 [Abstract] [Full Text] [PDF]   Brief report  Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl Christopher Slape, Leah Y. Liu, Sarah Beachy, and Peter D. Aplan Blood 2008 112: 2017-2019. Prepublished online June 19, 2008; DOI 10.1182/blood-2008-01-135186 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Brief report  mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia David T. Teachey, Cecilia Sheen, Junior Hall, Theresa Ryan, Valerie I. Brown, Jonathan Fish, Gregor S. D. Reid, Alix E. Seif, Robin Norris, Yueh J. Chang, Martin Carroll, and Stephan A. Grupp Blood 2008 112: 2020-2023. Prepublished online June 10, 2008; DOI 10.1182/blood-2008-02-137141 [Abstract] [Full Text] [PDF] [Supplemental Table]   Brief report  Multidrug resistance gene (MDR1) polymorphisms are associated with major molecular responses to standard-dose imatinib in chronic myeloid leukemia Stéphanie Dulucq, Stéphane Bouchet, Béatrice Turcq, Eric Lippert, Gabriel Etienne, Josy Reiffers, Mathieu Molimard, Maja Krajinovic, and François-Xavier Mahon Blood 2008 112: 2024-2027. Prepublished online June 4, 2008; DOI 10.1182/blood-2008-03-147744 [Abstract] [Full Text] [PDF]   PHAGOCYTES: Toll-like receptor–mediated activation of neutrophils by influenza A virus Jennifer P. Wang, Glennice N. Bowen, Carolyn Padden, Anna Cerny, Robert W. Finberg, Peter E. Newburger, and Evelyn A. Kurt-Jones Blood 2008 112: 2028-2034. Prepublished online June 10, 2008; DOI 10.1182/blood-2008-01-132860 [Abstract] [Full Text] [PDF]   Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow Jonathan J. Miner, Lijun Xia, Tadayuki Yago, János Kappelmayer, Zhenghui Liu, Arkadiusz G. Klopocki, Bojing Shao, J. Michael McDaniel, Hendra Setiadi, David W. Schmidtke, and Rodger P. McEver Blood 2008 112: 2035-2045. Prepublished online June 11, 2008; DOI 10.1182/blood-2008-04-149468 [Abstract] [Full Text] [PDF]   Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3 Bram J. van Raam, Agata Drewniak, Vincent Groenewold, Timo K. van den Berg, and Taco W. Kuijpers Blood 2008 112: 2046-2054. Prepublished online June 4, 2008; DOI 10.1182/blood-2008-04-149575 [Abstract] [Full Text] [PDF]   RED CELLS: A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function Inbal Lasry, Bluma Berman, Rachel Straussberg, Yael Sofer, Hanna Bessler, Mohamad Sharkia, Fabian Glaser, Gerrit Jansen, Stavit Drori, and Yehuda G. Assaraf Blood 2008 112: 2055-2061. Prepublished online June 17, 2008; DOI 10.1182/blood-2008-04-150276 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   HES1 is a novel interactor of the Fanconi anemia core complex Cédric S. Tremblay, Feng F. Huang, Ouassila Habi, Caroline C. Huard, Chantal Godin, Georges Lévesque, and Madeleine Carreau Blood 2008 112: 2062-2070. Prepublished online June 11, 2008; DOI 10.1182/blood-2008-04-152710 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression Bing-Mei Zhu, Sara K. McLaughlin, Risu Na, Jie Liu, Yongzhi Cui, Cyril Martin, Akiko Kimura, Gertraud W. Robinson, Nancy C. Andrews, and Lothar Hennighausen Blood 2008 112: 2071-2080. Prepublished online June 13, 2008; DOI 10.1182/blood-2007-12-127480 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype Belinda K. Singleton, Nicholas M. Burton, Carole Green, R. Leo Brady, and David J. Anstee Blood 2008 112: 2081-2088. Prepublished online May 16, 2008; DOI 10.1182/blood-2008-03-145672 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figure]   Brief report  Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency Flavia Guillem, Sarah Lawson, Caroline Kannengiesser, Mark Westerman, Carole Beaumont, and Bernard Grandchamp Blood 2008 112: 2089-2091. Prepublished online July 2, 2008; DOI 10.1182/blood-2008-05-154740 [Abstract] [Full Text] [PDF] [Supplemental Table]   TRANSFUSION MEDICINE: Donor demographic and laboratory predictors of allogeneic peripheral blood stem cell mobilization in an ethnically diverse population Sumithira Vasu, Susan F. Leitman, John F. Tisdale, Matthew M. Hsieh, Richard W. Childs, A. John Barrett, Daniel H. Fowler, Michael R. Bishop, Elizabeth M. Kang, Harry L. Malech, Cynthia E. Dunbar, Hanh M. Khuu, Robert Wesley, Yu Y. Yau, and Charles D. Bolan Blood 2008 112: 2092-2100. Prepublished online June 3, 2008; DOI 10.1182/blood-2008-03-143677 [Abstract] [Full Text] [PDF]   TRANSPLANTATION: Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease Tangsheng Yi, Dongchang Zhao, Chia-Lei Lin, Chunyan Zhang, Ying Chen, Ivan Todorov, Thomas LeBon, Fouad Kandeel, Stephen Forman, and Defu Zeng Blood 2008 112: 2101-2110. Prepublished online July 2, 2008; DOI 10.1182/blood-2007-12-126987 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Graft-versus-host disease causes failure of donor hematopoiesis and lymphopoiesis in interferon- receptor-deficient hosts Jean-Sébastien Delisle, Louis Gaboury, Marie-Pier Bélanger, Éliane Tassé, Hideo Yagita, and Claude Perreault Blood 2008 112: 2111-2119. Prepublished online June 13, 2008; DOI 10.1182/blood-2007-12-130534 [Abstract] [Full Text] [PDF] [Supplemental Table]   Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation Charles G. Mullighan, Susan L. Heatley, Silke Danner, Melinda M. Dean, Kathleen Doherty, Uwe Hahn, Kenneth F. Bradstock, Robyn Minchinton, Anthony P. Schwarer, Jeff Szer, and Peter G. Bardy Blood 2008 112: 2120-2128. Prepublished online June 13, 2008; DOI 10.1182/blood-2007-07-100222 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   In vivo–activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease Dongchang Zhao, Chunyan Zhang, Tangsheng Yi, Chia-Lei Lin, Ivan Todorov, Fouad Kandeel, Stephen Forman, and Defu Zeng Blood 2008 112: 2129-2138. Prepublished online June 12, 2008; DOI 10.1182/blood-2008-02-140277 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Angiopoietin-2 predicts disease-free survival after allogeneic stem cell transplantation in patients with high-risk myeloid malignancies Philipp Kümpers, Christian Koenecke, Hartmut Hecker, Julian Hellpap, Rüdiger Horn, Willem Verhagen, Stefanie Buchholz, Bernd Hertenstein, Jürgen Krauter, Matthias Eder, Sascha David, Gudrun Göhring, Hermann Haller, and Arnold Ganser Blood 2008 112: 2139-2148. Prepublished online May 15, 2008; DOI 10.1182/blood-2007-12-130021 [Abstract] [Full Text] [PDF]   Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway Fabienne Haspot, Thomas Fehr, Carrie Gibbons, Guiling Zhao, Timothy Hogan, Tasuku Honjo, Gordon J. Freeman, and Megan Sykes Blood 2008 112: 2149-2155. Prepublished online June 24, 2008; DOI 10.1182/blood-2007-12-127449 [Abstract] [Full Text] [PDF] [Supplemental Tables]   Brief report  A single nucleotide polymorphism at chromosome 2q21.3 (LCT –13910C>T) associates with clinical outcome after allogeneic hematopoietic stem cell transplantation Hanns Hauser, Otto Zach, Otto Krieger, Hedwig Kasparu, Josef Koenig, Michael Girschikofsky, Rainer Oberbauer, and Dieter Lutz Blood 2008 112: 2156-2159. Prepublished online June 10, 2008; DOI 10.1182/blood-2008-02-139766 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  Expansion of donor-derived hematopoietic stem cells with PIGA mutation associated with late graft failure after allogeneic stem cell transplantation Kanako Mochizuki, Chiharu Sugimori, Zhirong Qi, Xuzhang Lu, Akiyoshi Takami, Ken Ishiyama, Yukio Kondo, Hirohito Yamazaki, Hirokazu Okumura, and Shinji Nakao Blood 2008 112: 2160-2162. Prepublished online July 2, 2008; DOI 10.1182/blood-2008-02-141325 [Abstract] [Full Text] [PDF] [Supplemental Table]   Brief report  Association between BMI-1 expression, acute graft-versus-host disease, and outcome following allogeneic stem cell transplantation from HLA-identical siblings in chronic myeloid leukemia Mohamad Mohty, Richard M. Szydlo, Agnes S. M. Yong, Jane F. Apperley, John M. Goldman, and Junia V. Melo Blood 2008 112: 2163-2166. Prepublished online June 18, 2008; DOI 10.1182/blood-2008-04-148130 [Abstract] [Full Text] [PDF]   CORRESPONDENCE: Valganciclovir versus valaciclovir for prevention of alemtuzumab-induced cytomegalovirus reactivation: what are the implications for routine clinical practice? Lukas Smolej Blood 2008 112: 2167. [Full Text] [PDF]   SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a Irina Seyfried, Sebastian Hofbauer, Markus Stoecher, Richard Greil, and Inge Tinhofer Blood 2008 112: 2168. [Full Text] [PDF]   MDM2-SNP 309 allele status does not affect sensitivity to MDM2 inhibitors in CLL Sami N. Malek Blood 2008 112: 2169. [Full Text] [PDF]   ERRATUM: Strasly et al. CCL16 activates an angiogenic program in vascular endothelial cells. Blood. 2004;103:40-49. Blood 2008 112: 2170. [Full Text] [PDF]   Colla et al. The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 (HIF-1) activity: involvement in myeloma-induced angiogenesis. Blood. 2007;110:4464-4475. Blood 2008 112: 2170. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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