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Receive this page by email each issue: [Sign up for eTOCs] Other Issues: September 1 2007; 110 (5)   [Index by Author]  [Cover Caption]  [Complete Inside Blood PDF]         INSIDE BLOOD        BLOOD WORK        REVIEW IN TRANSLATIONAL HEMATOLOGY        CHEMOKINES, CYTOKINES, AND INTERLEUKINS        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS        HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY        IMMUNOBIOLOGY        NEOPLASIA        TRANSPLANTATION        CORRESPONDENCE        ERRATUM Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Treating AML with ATRA? Beware MN1! Gerard C. Grosveld Blood 2007 110: 1401-1402. [Full Text] [PDF]   Connecting ribosomes with bone marrow failure Stefan Karlsson Blood 2007 110: 1402. [Full Text] [PDF]   MEK inhibitor: the MM magic bullet? Bruno Quesnel Blood 2007 110: 1402-1403. [Full Text] [PDF]   SOCS box: fine-tuning inflammatory responses Robert P. Coppes Blood 2007 110: 1403-1404. [Full Text] [PDF]   Possible requiem: trial-and-error warfarin Samuel Z. Goldhaber Blood 2007 110: 1404-1405. [Full Text] [PDF]   ß2-GPI dampening of VWF-GPIb interaction Robert R. Montgomery Blood 2007 110: 1405. [Full Text] [PDF]   Viral infections: beneficial role of eosinophils Richard L. Stevens Blood 2007 110: 1406. [Full Text] [PDF]   Suppression, surprise: galectin-10 and Treg cells Helene F. Rosenberg Blood 2007 110: 1407-1408. [Full Text] [PDF]   CD4+ T cells don't always help Christoph Neumann-Haefelin and Robert Thimme Blood 2007 110: 1408-1409. [Full Text] [PDF]   Methuselah conundrum: MPDs in the elderly Peter J. Campbell and Anthony R. Green Blood 2007 110: 1409. [Full Text] [PDF]   BLOOD WORK: Splenic villous lymphoma—peripheral blood Peter Maslak Blood 2007 110: 1410. [Full Text] [PDF]   REVIEW IN TRANSLATIONAL HEMATOLOGY: X-linked clonality testing: interpretation and limitations George L. Chen and Josef T. Prchal Blood 2007 110: 1411-1419. Prepublished online April 13, 2007; DOI 10.1182/blood-2006-09-018655 [Abstract] [Full Text] [PDF]   CHEMOKINES, CYTOKINES, AND INTERLEUKINS: Activation of mitogen-activated protein kinase kinase (MEK)/extracellular signal–regulated kinase (ERK) signaling pathway is involved in myeloid lineage commitment Chia-Lin Hsu, Kazu Kikuchi, and Motonari Kondo Blood 2007 110: 1420-1428. Prepublished online May 29, 2007; DOI 10.1182/blood-2007-02-071761 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   CLINICAL TRIALS AND OBSERVATIONS: Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group Stuart S. Winter, Zeyu Jiang, Hadya M. Khawaja, Timothy Griffin, Meenakshi Devidas, Barbara L. Asselin, and Richard S. Larson Blood 2007 110: 1429-1438. Prepublished online May 10, 2007; DOI 10.1182/blood-2006-12-059790 [Abstract] [Full Text] [PDF] [Supplemental Appendix and Tables][Supplemental Figures]   Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita Blanche P. Alter, Gabriela M. Baerlocher, Sharon A. Savage, Stephen J. Chanock, Babette B. Weksler, Judith P. Willner, June A. Peters, Neelam Giri, and Peter M. Lansdorp Blood 2007 110: 1439-1447. Prepublished online April 27, 2007; DOI 10.1182/blood-2007-02-075598 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figure]   GENE THERAPY: Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells Fang Zhang, Susannah I. Thornhill, Steven J. Howe, Meera Ulaganathan, Axel Schambach, Joanna Sinclair, Christine Kinnon, H. Bobby Gaspar, Michael Antoniou, and Adrian J. Thrasher Blood 2007 110: 1448-1457. Prepublished online April 24, 2007; DOI 10.1182/blood-2006-12-060814 [Abstract] [Full Text] [PDF] [Supplemental Figures]   HEMATOPOIESIS: The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNA Karthik A. Ganapathi, Karyn M. Austin, Chung-Sheng Lee, Anusha Dias, Maggie M. Malsch, Robin Reed, and Akiko Shimamura Blood 2007 110: 1458-1465. Prepublished online May 2, 2007; DOI 10.1182/blood-2007-02-075184 [Abstract] [Full Text] [PDF] [Supplemental Table]   The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo Kristy Boyle, Paul Egan, Steven Rakar, Tracy A. Willson, Ian P. Wicks, Donald Metcalf, Douglas J. Hilton, Nicos A. Nicola, Warren S. Alexander, Andrew W. Roberts, and Lorraine Robb Blood 2007 110: 1466-1474. Prepublished online May 17, 2007; DOI 10.1182/blood-2007-03-079178 [Abstract] [Full Text] [PDF] [Supplemental Figure]   HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY: Thrombin regulates intracellular cyclic AMP concentration in human platelets through phosphorylation/activation of phosphodiesterase 3A Wei Zhang and Robert W. Colman Blood 2007 110: 1475-1482. Prepublished online March 28, 2007; DOI 10.1182/blood-2006-10-052522 [Abstract] [Full Text] [PDF]   ß2-Glycoprotein I inhibits von Willebrand factor–dependent platelet adhesion and aggregation Janine J. J. Hulstein, Peter J. Lenting, Bas de Laat, Ron H. W. M. Derksen, Rob Fijnheer, and Philip G. de Groot Blood 2007 110: 1483-1491. Prepublished online May 8, 2007; DOI 10.1182/blood-2006-10-053199 [Abstract] [Full Text] [PDF]   SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane Robert Flaumenhaft, Nataliya Rozenvayn, Dian Feng, and Ann M. Dvorak Blood 2007 110: 1492-1501. Prepublished online May 7, 2007; DOI 10.1182/blood-2006-11-055772 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity Dong Liu, Jian Wang, Bernd Kinzel, Matthias Müeller, Xiaohong Mao, Reginald Valdez, Yongxing Liu, and En Li Blood 2007 110: 1502-1510. Prepublished online May 11, 2007; DOI 10.1182/blood-2006-11-058594 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Genetic-based dosing in orthopedic patients beginning warfarin therapy Eric A. Millican, Petra A. Lenzini, Paul E. Milligan, Leonard Grosso, Charles Eby, Elena Deych, Gloria Grice, John C. Clohisy, Robert L. Barrack, R. Stephen J. Burnett, Deepak Voora, Susan Gatchel, Amy Tiemeier, and Brian F. Gage Blood 2007 110: 1511-1515. Prepublished online March 26, 2007; DOI 10.1182/blood-2007-01-069609 [Abstract] [Full Text] [PDF]   Brief report  Anti–factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome Mihály Józsi, Stefanie Strobel, Hans-Martin Dahse, Wei-shih Liu, Peter F. Hoyer, Martin Oppermann, Christine Skerka, and Peter F. Zipfel Blood 2007 110: 1516-1518. Prepublished online May 10, 2007; DOI 10.1182/blood-2007-02-071472 [Abstract] [Full Text] [PDF] [Supplemental Figures]   IMMUNOBIOLOGY: Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse Peter Reichardt, Bastian Dornbach, Song Rong, Stefan Beissert, Faikah Gueler, Karin Loser, and Matthias Gunzer Blood 2007 110: 1519-1529. Prepublished online March 28, 2007; DOI 10.1182/blood-2006-10-053793 [Abstract] [Full Text] [PDF]   The unexpected effect of cyclosporin A on CD56+CD16– and CD56+CD16+ natural killer cell subpopulations Hongbo Wang, Bartosz Grzywacz, David Sukovich, Valarie McCullar, Qing Cao, Alisa B. Lee, Bruce R. Blazar, David N. Cornfield, Jeffrey S. Miller, and Michael R. Verneris Blood 2007 110: 1530-1539. Prepublished online May 10, 2007; DOI 10.1182/blood-2006-10-048173 [Abstract] [Full Text] [PDF]   Noncanonical NF-B signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation Sander W. Tas, Margriet J. Vervoordeldonk, Najat Hajji, Joost H. N. Schuitemaker, Koen F. van der Sluijs, Michael J. May, Sankar Ghosh, Martien L. Kapsenberg, Paul P. Tak, and Esther C. de Jong Blood 2007 110: 1540-1549. Prepublished online May 4, 2007; DOI 10.1182/blood-2006-11-056010 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function Jan Kubach, Petra Lutter, Tobias Bopp, Sabine Stoll, Christian Becker, Eva Huter, Christoph Richter, Petra Weingarten, Tobias Warger, Jürgen Knop, Stefan Müllner, John Wijdenes, Hansjörg Schild, Edgar Schmitt, and Helmut Jonuleit Blood 2007 110: 1550-1558. Prepublished online May 14, 2007; DOI 10.1182/blood-2007-01-069229 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non–genotype 1 infection Julian Schulze zur Wiesch, Georg M. Lauer, Joerg Timm, Thomas Kuntzen, Martin Neukamm, Andrew Berical, Andrea M. Jones, Brian E. Nolan, Steve A. Longworth, Victoria Kasprowicz, Cory McMahon, Alysse Wurcel, Ansgar W. Lohse, Lia L. Lewis-Ximenez, Raymond T. Chung, Arthur Y. Kim, Todd M. Allen, and Bruce D. Walker Blood 2007 110: 1559-1569. Prepublished online May 2, 2007; DOI 10.1182/blood-2007-01-069583 [Abstract] [Full Text] [PDF]   ATF2 impairs glucocorticoid receptor–mediated transactivation in human CD8+ T cells Ling-bo Li, Donald Y. M. Leung, Matthew J. Strand, and Elena Goleva Blood 2007 110: 1570-1577. Prepublished online May 24, 2007; DOI 10.1182/blood-2007-01-070755 [Abstract] [Full Text] [PDF]   Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus Simon Phipps, Chuan En Lam, Suresh Mahalingam, Matthew Newhouse, Ruben Ramirez, Helene F. Rosenberg, Paul S. Foster, and Klaus I. Matthaei Blood 2007 110: 1578-1586. Prepublished online May 10, 2007; DOI 10.1182/blood-2007-01-071340 [Abstract] [Full Text] [PDF]   Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma Jianfei Qian, Jin Xie, Sungyoul Hong, Jing Yang, Liang Zhang, Xiaohong Han, Michael Wang, Fenghuang Zhan, John D. Shaughnessy, Jr, Joshua Epstein, Larry W. Kwak, and Qing Yi Blood 2007 110: 1587-1594. Prepublished online May 21, 2007; DOI 10.1182/blood-2007-03-082529 [Abstract] [Full Text] [PDF]   Macrophages prevent the differentiation of autoreactive B cells by secreting CD40 ligand and interleukin-6 Michelle A. Kilmon, Nikki J. Wagner, Alaina L. Garland, Li Lin, Katja Aviszus, Lawrence J. Wysocki, and Barbara J. Vilen Blood 2007 110: 1595-1602. Prepublished online June 1, 2007; DOI 10.1182/blood-2006-12-061648 [Abstract] [Full Text] [PDF]   Brief report  Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia Elena E. Solomou, Katayoun Rezvani, Stephan Mielke, Daniela Malide, Keyvan Keyvanfar, Valeria Visconte, Sachiko Kajigaya, A. John Barrett, and Neal S. Young Blood 2007 110: 1603-1606. Prepublished online April 26, 2007; DOI 10.1182/blood-2007-01-066258 [Abstract] [Full Text] [PDF] [Supplemental Methods, Table, and Figures]   NEOPLASIA: Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01 Jianbiao Zhou, Meredith A Goldwasser, Aihong Li, Suzanne E. Dahlberg, Donna Neuberg, Hongjun Wang, Virginia Dalton, Kathryn D McBride, Stephen E. Sallan, Lewis B Silverman, and John G. Gribben, for the Dana-Farber Cancer Institute ALL Consortium Blood 2007 110: 1607-1611. Prepublished online May 7, 2007; DOI 10.1182/blood-2006-09-045369 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Genetic and pharmacologic evidence implicating the p85, but not p85ß, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis Veerendra Munugalavadla, Emily C. Sims, Jovencio Borneo, Rebecca J. Chan, and Reuben Kapur Blood 2007 110: 1612-1620. Prepublished online May 4, 2007; DOI 10.1182/blood-2006-10-053058 [Abstract] [Full Text] [PDF]   NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma Vasiliki Leventaki, Elias Drakos, L. Jeffrey Medeiros, Megan S. Lim, Kojo S. Elenitoba-Johnson, Francois X. Claret, and George Z. Rassidakis Blood 2007 110: 1621-1630. Prepublished online April 6, 2007; DOI 10.1182/blood-2006-11-059451 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas Tint Lwin, Lori A. Hazlehurst, Sophie Dessureault, Raymond Lai, Wenlong Bai, Eduardo Sotomayor, Lynn C. Moscinski, William S. Dalton, and Jianguo Tao Blood 2007 110: 1631-1638. Prepublished online May 14, 2007; DOI 10.1182/blood-2006-11-060350 [Abstract] [Full Text] [PDF]   MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML Michael Heuser, Bob Argiropoulos, Florian Kuchenbauer, Eric Yung, Jessica Piper, Stephen Fung, Richard F. Schlenk, Konstanze Dohner, Tanja Hinrichsen, Cornelia Rudolph, Axel Schambach, Christopher Baum, Brigitte Schlegelberger, Hartmut Dohner, Arnold Ganser, and R. Keith Humphries Blood 2007 110: 1639-1647. Prepublished online May 9, 2007; DOI 10.1182/blood-2007-03-080523 [Abstract] [Full Text] [PDF] [Supplemental Tables][Supplemental Figures]   Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia Daniel C. Link, Ghada Kunter, Yumi Kasai, Yu Zhao, Tracie Miner, Michael D. McLellan, Rhonda E. Ries, Deepak Kapur, Rakesh Nagarajan, David C. Dale, Audrey Anna Bolyard, Laurence A. Boxer, Karl Welte, Cornelia Zeidler, Jean Donadieu, Christine Bellanné-Chantelot, James W. Vardiman, Michael A. Caligiuri, Clara D. Bloomfield, John F. DiPersio, Michael H. Tomasson, Timothy A. Graubert, Peter Westervelt, Mark Watson, William Shannon, Jack Baty, Elaine R. Mardis, Richard K. Wilson, and Timothy J. Ley Blood 2007 110: 1648-1655. Prepublished online May 9, 2007; DOI 10.1182/blood-2007-03-081216 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis Yu-Tzu Tai, Mariateresa Fulciniti, Teru Hideshima, Weihua Song, Merav Leiba, Xian-Feng Li, Matthew Rumizen, Peter Burger, Aileen Morrison, Klaus Podar, Dharminder Chauhan, Pierfrancesco Tassone, Paul Richardson, Nikhil C. Munshi, Irene M. Ghobrial, and Kenneth C. Anderson Blood 2007 110: 1656-1663. Prepublished online May 17, 2007; DOI 10.1182/blood-2007-03-081240 [Abstract] [Full Text] [PDF] [Supplemental Figure]   A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) through 15-deoxy-12, 14 prostaglandin J2 production Hiroo Hasegawa, Yasuaki Yamada, Kanki Komiyama, Masahiko Hayashi, Masami Ishibashi, Toshiaki Sunazuka, Takeshi Izuhara, Kazuyuki Sugahara, Kazuto Tsuruda, Masato Masuda, Nobuyuki Takasu, Kunihiro Tsukasaki, Masao Tomonaga, and Shimeru Kamihira Blood 2007 110: 1664-1674. Prepublished online June 5, 2007; DOI 10.1182/blood-2007-01-068981 [Abstract] [Full Text] [PDF]   JAK2 617V>F–positive polycythemia rubra vera maintained by approximately 18 stochastic stem-cell divisions per year, explaining age of onset by a single rate-limiting mutation Mark A. Vickers Blood 2007 110: 1675-1680. Prepublished online April 23, 2007; DOI 10.1182/blood-2006-12-061911 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   TRANSPLANTATION: Respiratory virus infection among hematopoietic cell transplant recipients: evidence for asymptomatic parainfluenza virus infection Angela J. Peck, Janet A. Englund, Jane Kuypers, Katherine A. Guthrie, Lawrence Corey, Rhoda Morrow, Robert C. Hackman, Anne Cent, and Michael Boeckh Blood 2007 110: 1681-1688. Prepublished online May 14, 2007; DOI 10.1182/blood-2006-12-060343 [Abstract] [Full Text] [PDF]   Reconstitution of FOXP3+ regulatory T cells (Tregs) after CD25-depleted allotransplantion in elderly patients and association with acute graft-versus-host disease Stephan Mielke, Katayoun Rezvani, Bipin N. Savani, Raquel Nunes, Agnes S. M. Yong, John Schindler, Roger Kurlander, Victor Ghetie, Elizabeth J. Read, Scott R. Solomon, Ellen S. Vitetta, and A. John Barrett Blood 2007 110: 1689-1697. Prepublished online May 3, 2007; DOI 10.1182/blood-2007-03-079160 [Abstract] [Full Text] [PDF]   CORRESPONDENCE: Neurologic complications associated with intrathecal liposomal cytarabine given prophylactically in combination with high-dose methotrexate and cytarabine to patients with acute lymphocytic leukemia Marc C. Chamberlain and Michael J. Glantz Blood 2007 110: 1698. [Full Text] [PDF]   Neurologic toxicity of intrathecal liposomal cytarabine when used for CNS prophylaxis in conjunction with the hyper-CVAD regimen Deborah A. Thomas, Elias Jabbour, Hagop Kantarjian, and Susan O'Brien Blood 2007 110: 1698-1699. [Full Text] [PDF]   Therapeutic drug monitoring in CML patients on imatinib Carolyn Blasdel, Merrill J. Egorin, Theodore F. Lagattuta, Brian J. Druker, and Michael W. Deininger Blood 2007 110: 1699-1701. [Full Text] [PDF]   Use of therapeutic drug monitoring in CML patients on imatinib François-Xavier Mahon, Stéphane Picard, Gerald Marit, Philip Robinson, and Mathieu Molimard Blood 2007 110: 1701. [Full Text] [PDF]   ERRATUM: Erratum for Spivak et al Thrombocytosis, pregnancy, and regression toward mean Blood 2007 110: 1419. [Full Text] [PDF]   Erratum for Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy Blood 2007 110: 1438. [Full Text] [PDF]   Erratum for Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness Blood 2007 110: 1474. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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