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Receive this page by email each issue: [Sign up for eTOCs] Other Issues: November 15 2007; 110 (10)   [Index by Author]  [Cover Caption]  [Complete Inside Blood PDF]         INSIDE BLOOD        REVIEW IN TRANSLATIONAL HEMATOLOGY        CHEMOKINES, CYTOKINES, AND INTERLEUKINS        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS        HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY        IMMUNOBIOLOGY        NEOPLASIA        PHAGOCYTES        RED CELLS        TRANSPLANTATION        CORRESPONDENCE Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Lycat: new targets in hemangioblast differentiation? Burcin Özüyaman and Malte Kelm Blood 2007 110: 3489. [Full Text] [PDF]   Amyloidosis: graviores morbos, asperis remedii Jayesh Mehta Blood 2007 110: 3490-3491. [Full Text] [PDF]   AML: treatment-related toxicity or not? Giuseppe Avvisati Blood 2007 110: 3491. [Full Text] [PDF]   Taxol therapy revisited Shida Yousefi and Hans-Uwe Simon Blood 2007 110: 3492. [Full Text] [PDF]   A wrinkle in the unfolding of hypoxic response: HIF and ATF4 Alexander Weidemann and Randall S. Johnson Blood 2007 110: 3492-3493. [Full Text] [PDF]   Hematopoietic cell transplantation: a lifelong commitment André Tichelli Blood 2007 110: 3493-3494. [Full Text] [PDF]   Viral mimic for B-cell survival Ralf Küppers Blood 2007 110: 3494-3495. [Full Text] [PDF]   Hyperhomocysteinemia: DNA hypomethylation and endothelial degeneration Ming-Hui Zou Blood 2007 110: 3495-3496. [Full Text] [PDF]   Rap1: selective activator of ß2 integrins? Philip J. S. Stork Blood 2007 110: 3496-3497. [Full Text] [PDF]   Regulatory T cells and the pursuit of self-tolerance Allan D. Hess Blood 2007 110: 3497-3498. [Full Text] [PDF]   REVIEW IN TRANSLATIONAL HEMATOLOGY: Immunomodulatory properties of mesenchymal stromal cells Alma J. Nauta and Willem E. Fibbe Blood 2007 110: 3499-3506. Prepublished online July 30, 2007; DOI 10.1182/blood-2007-02-069716 [Abstract] [Full Text] [PDF]   The role of FDG-PET scans in patients with lymphoma Pamela Seam, Malik E. Juweid, and Bruce D. Cheson Blood 2007 110: 3507-3516. Prepublished online August 20, 2007; DOI 10.1182/blood-2007-06-097238 [Abstract] [Full Text] [PDF]   CHEMOKINES, CYTOKINES, AND INTERLEUKINS: Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-B signaling pathway Manoj K. Pandey, Bokyung Sung, Kwang Seok Ahn, Ajaikumar B. Kunnumakkara, Madan M. Chaturvedi, and Bharat B. Aggarwal Blood 2007 110: 3517-3525. Prepublished online August 2, 2007; DOI 10.1182/blood-2007-03-079616 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP) Donna M. Boruchov, Sri Gururangan, M. Catherine Driscoll, and James B. Bussel Blood 2007 110: 3526-3531. Prepublished online August 13, 2007; DOI 10.1182/blood-2007-01-065763 [Abstract] [Full Text] [PDF]   Microbiologically documented infections and infection-related mortality in children with acute myeloid leukemia Lillian Sung, Beverly J. Lange, Robert B. Gerbing, Todd A. Alonzo, and James Feusner Blood 2007 110: 3532-3539. Prepublished online July 27, 2007; DOI 10.1182/blood-2007-05-091942 [Abstract] [Full Text] [PDF]   Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome–positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance Hagop M. Kantarjian, Francis Giles, Norbert Gattermann, Kapil Bhalla, Giuliana Alimena, Francesca Palandri, Gert J. Ossenkoppele, Franck-Emmanuel Nicolini, Stephen G. O'Brien, Mark Litzow, Ravi Bhatia, Francisco Cervantes, Ariful Haque, Yaping Shou, Debra J. Resta, Aaron Weitzman, Andreas Hochhaus, and Philipp le Coutre Blood 2007 110: 3540-3546. Prepublished online August 22, 2007; DOI 10.1182/blood-2007-03-080689 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Establishment of baseline toxicity expectations with standard frontline chemotherapy in acute myelogenous leukemia Ehab Atallah, Jorge Cortes, Susan O'Brien, Sherry Pierce, Mary Beth Rios, Elihu Estey, Maurie Markman, Michael Keating, Emil J. Freireich, and Hagop Kantarjian Blood 2007 110: 3547-3551. Prepublished online August 2, 2007; DOI 10.1182/blood-2007-06-095844 [Abstract] [Full Text] [PDF]   Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosing Amy D. Klion, Jamie Robyn, Irina Maric, Weiming Fu, Laura Schmid, Steven Lemery, Pierre Noel, Melissa A. Law, Marilyn Hartsell, Cheryl Talar-Williams, Michael P. Fay, Cynthia E. Dunbar, and Thomas B. Nutman Blood 2007 110: 3552-3556. Prepublished online August 20, 2007; DOI 10.1182/blood-2007-07-100164 [Abstract] [Full Text] [PDF]   Brief report  Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial Paul G. Richardson, Pieter Sonneveld, Michael Schuster, David Irwin, Edward Stadtmauer, Thierry Facon, Jean-Luc Harousseau, Dina Ben-Yehuda, Sagar Lonial, Hartmut Goldschmidt, Donna Reece, Jesus San Miguel, Joan Bladé, Mario Boccadoro, Jamie Cavenagh, Melissa Alsina, S. Vincent Rajkumar, Martha Lacy, Andrzej Jakubowiak, William Dalton, Anthony Boral, Dixie-Lee Esseltine, David Schenkein, and Kenneth C. Anderson Blood 2007 110: 3557-3560. Prepublished online August 9, 2007; DOI 10.1182/blood-2006-08-036947 [Abstract] [Full Text] [PDF] [Supplemental Appendices]   Brief report  Long-term outcome of patients with AL amyloidosis treated with high-dose melphalan and stem-cell transplantation Vaishali Sanchorawala, Martha Skinner, Karen Quillen, Kathleen T. Finn, Gheorghe Doros, and David C. Seldin Blood 2007 110: 3561-3563. Prepublished online August 2, 2007; DOI 10.1182/blood-2007-07-099481 [Abstract] [Full Text] [PDF]   GENE THERAPY: Selecting highly affine and well-expressed TCRs for gene therapy of melanoma Annelies Jorritsma, Raquel Gomez-Eerland, Maarten Dokter, Willeke van de Kasteele, Yvonne M. Zoet, Ilias I. N. Doxiadis, Nathalie Rufer, Pedro Romero, Richard A. Morgan, Ton N. M. Schumacher, and John B. A. G. Haanen Blood 2007 110: 3564-3572. Prepublished online July 27, 2007; DOI 10.1182/blood-2007-02-075010 [Abstract] [Full Text] [PDF] [Supplemental Figures]   HEMATOPOIESIS: Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene Jessica M. Salmon, Nicholas J. Slater, Mark A. Hall, Matthew P. McCormack, Stephen L. Nutt, Stephen M. Jane, and David J. Curtis Blood 2007 110: 3573-3581. Prepublished online July 20, 2007; DOI 10.1182/blood-2006-10-053124 [Abstract] [Full Text] [PDF]   The Shc-binding site of the ßc subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis Hayley S. Ramshaw, Mark A. Guthridge, Frank C. Stomski, Emma F. Barry, Lisa Ooms, Christina A. Mitchell, C. Glenn Begley, and Angel F. Lopez Blood 2007 110: 3582-3590. Prepublished online July 16, 2007; DOI 10.1182/blood-2007-01-070391 [Abstract] [Full Text] [PDF] [Supplemental Figure]   The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways Fumihiko Ishikawa, Hiroaki Niiro, Tadafumi Iino, Shuro Yoshida, Noriyuki Saito, Shinya Onohara, Toshihiro Miyamoto, Hiroko Minagawa, Shin-ichiro Fujii, Leonard D. Shultz, Mine Harada, and Koichi Akashi Blood 2007 110: 3591-3660. Prepublished online July 30, 2007; DOI 10.1182/blood-2007-02-071613 [Abstract] [Full Text] [PDF]   Mouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation Chengyan Wang, Patrick W. Faloon, Zhijia Tan, Yaxin Lv, Pengbo Zhang, Yu Ge, Hongkui Deng, and Jing-Wei Xiong Blood 2007 110: 3601-3609. Prepublished online August 3, 2007; DOI 10.1182/blood-2007-04-086827 [Abstract] [Full Text] [PDF] [Supplemental Tables]   Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor Jens Köditz, Jutta Nesper, Marieke Wottawa, Daniel P. Stiehl, Gieri Camenisch, Corinna Franke, Johanna Myllyharju, Roland H. Wenger, and Dörthe M. Katschinski Blood 2007 110: 3610-3617. Prepublished online August 7, 2007; DOI 10.1182/blood-2007-06-094441 [Abstract] [Full Text] [PDF]   The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development Lizi Wu, Ivan Maillard, Makoto Nakamura, Warren S. Pear, and James D. Griffin Blood 2007 110: 3618-3623. Prepublished online August 15, 2007; DOI 10.1182/blood-2007-06-097030 [Abstract] [Full Text] [PDF]   Brief report  The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans Stephan Menzel, Jie Jiang, Nicholas Silver, Joy Gallagher, Juliette Cunningham, Gabriela Surdulescu, Mark Lathrop, Martin Farrall, Tim D. Spector, and Swee Lay Thein Blood 2007 110: 3624-3626. Prepublished online August 21, 2007; DOI 10.1182/blood-2007-05-093419 [Abstract] [Full Text] [PDF]   HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY: Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish Nathan Bahary, Katsutoshi Goishi, Carsten Stuckenholz, Gerhard Weber, Jocelyn LeBlanc, Christopher A. Schafer, Sarah S. Berman, Michael Klagsbrun, and Leonard I. Zon Blood 2007 110: 3627-3636. Prepublished online August 14, 2007; DOI 10.1182/blood-2006-04-016378 [Abstract] [Full Text] [PDF] [Supplemental Tables]   The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery Koji Eto, Hidekazu Nishikii, Takunori Ogaeri, Shiro Suetsugu, Akihide Kamiya, Toshihiro Kobayashi, Daisuke Yamazaki, Atsushi Oda, Tadaomi Takenawa, and Hiromitsu Nakauchi Blood 2007 110: 3637-3647. Prepublished online July 30, 2007; DOI 10.1182/blood-2007-04-085860 [Abstract] [Full Text] [PDF]   Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin Agene Md S. Jamaluddin, Irene Chen, Fan Yang, Xiaohua Jiang, Michael Jan, Xiaoming Liu, Andrew I. Schafer, William Durante, Xiaofeng Yang, and Hong Wang Blood 2007 110: 3648-3655. Prepublished online August 13, 2007; DOI 10.1182/blood-2007-06-096701 [Abstract] [Full Text] [PDF]   Delays in maturation among adolescents with hemophilia and a history of inhibitors Sharyne M. Donfield, Henry S. Lynn, Alice E. Lail, W. Keith Hoots, Erik Berntorp, and Edward D. Gomperts, for the Hemophilia Growth and Development Study Group Blood 2007 110: 3656-3661. Prepublished online August 22, 2007; DOI 10.1182/blood-2007-05-088062 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   IMMUNOBIOLOGY: Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment Katja Janssen, Stephan Pohlmann, Reiner U. Jänicke, Klaus Schulze-Osthoff, and Ute Fischer Blood 2007 110: 3662-3672. Prepublished online July 25, 2007; DOI 10.1182/blood-2007-02-073213 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figure]   Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis Philip O. Scumpia, Matthew J. Delano, Kindra M. Kelly-Scumpia, Jason S. Weinstein, James L. Wynn, Robert D. Winfield, Changqing Xia, Chun Shiang Chung, Alfred Ayala, Mark A. Atkinson, Westley H. Reeves, Michael J. Clare-Salzler, and Lyle L. Moldawer Blood 2007 110: 3673-3681. Prepublished online August 9, 2007; DOI 10.1182/blood-2007-04-087171 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin–mediated human T-cell adhesion Haifa Ghandour, Xavier Cullere, Angeles Alvarez, Francis W. Luscinskas, and Tanya N. Mayadas Blood 2007 110: 3682-3690. Prepublished online August 16, 2007; DOI 10.1182/blood-2007-03-077628 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells Dominique Chabannes, Marcelo Hill, Emmanuel Merieau, Julien Rossignol, Régis Brion, Jean Paul Soulillou, Ignacio Anegon, and Maria Cristina Cuturi Blood 2007 110: 3691-3694. Prepublished online August 7, 2007; DOI 10.1182/blood-2007-02-075481 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   NEOPLASIA: CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer–binding protein alpha Steffen Koschmieder, Francesco D'Alò, Hanna Radomska, Christine Schöneich, Ji Suk Chang, Marina Konopleva, Susumu Kobayashi, Elena Levantini, Nanjoo Suh, Annalisa Di Ruscio, Maria Teresa Voso, Julie C. Watt, Ramasamy Santhanam, Bülent Sargin, Hagop Kantarjian, Michael Andreeff, Michael B. Sporn, Danilo Perrotti, Wolfgang E. Berdel, Carsten Müller-Tidow, Hubert Serve, and Daniel G. Tenen Blood 2007 110: 3695-3705. Prepublished online August 1, 2007; DOI 10.1182/blood-2006-11-058941 [Abstract] [Full Text] [PDF] [Supplemental Table]   Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1 Bas J. Wouters, Meritxell Alberich Jordà, Karen Keeshan, Irene Louwers, Claudia A. J. Erpelinck-Verschueren, Dennis Tielemans, Anton W. Langerak, Yiping He, Yumi Yashiro-Ohtani, Pu Zhang, Christopher J. Hetherington, Roel G. W. Verhaak, Peter J. M. Valk, Bob Löwenberg, Daniel G. Tenen, Warren S. Pear, and Ruud Delwel Blood 2007 110: 3706-3714. Prepublished online August 1, 2007; DOI 10.1182/blood-2007-02-073486 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival Christoph Mancao and Wolfgang Hammerschmidt Blood 2007 110: 3715-3721. Prepublished online August 6, 2007; DOI 10.1182/blood-2007-05-090142 [Abstract] [Full Text] [PDF]   Histone deacetylase–mediated transcriptional activation reduces proviral loads in HTLV-1–associated myelopathy/tropical spastic paraparesis patients Agnès Lezin, Nicolas Gillet, Stéphane Olindo, Aïssatou Signaté, Nathalie Grandvaux, Olivier Verlaeten, Gildas Belrose, Marcelo de Carvalho Bittencourt, John Hiscott, Becca Asquith, Arsène Burny, Didier Smadja, Raymond Césaire, and Luc Willems Blood 2007 110: 3722-3728. Prepublished online August 23, 2007; DOI 10.1182/blood-2007-04-085076 [Abstract] [Full Text] [PDF]   Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome Andrew Chase, Francis H. Grand, and Nicholas C. P. Cross Blood 2007 110: 3729-3734. Prepublished online August 13, 2007; DOI 10.1182/blood-2007-02-074286 [Abstract] [Full Text] [PDF]   Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis Ronan Chaligné, Chloé James, Carole Tonetti, Rodolphe Besancenot, Jean Pierre Le Couédic, Fanny Fava, Fréderic Mazurier, Isabelle Godin, Karim Maloum, Frédéric Larbret, Yann Lécluse, William Vainchenker, and Stéphane Giraudier Blood 2007 110: 3735-3743. Prepublished online August 20, 2007; DOI 10.1182/blood-2007-05-089003 [Abstract] [Full Text] [PDF]   MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts Sonia Vallet, Noopur Raje, Kenji Ishitsuka, Teru Hideshima, Klaus Podar, Shweta Chhetri, Samantha Pozzi, Iris Breitkreutz, Tanyel Kiziltepe, Hiroshi Yasui, Enrique M. Ocio, Norihiko Shiraishi, Janice Jin, Yutaka Okawa, Hiroshi Ikeda, Siddhartha Mukherjee, Nileshwari Vaghela, Diana Cirstea, Marco Ladetto, Mario Boccadoro, and Kenneth C. Anderson Blood 2007 110: 3744-3752. Prepublished online August 22, 2007; DOI 10.1182/blood-2007-05-093294 [Abstract] [Full Text] [PDF] [Supplemental Figure]   NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis Joachim R. Göthert, Rachael L. Brake, Monique Smeets, Ulrich Dührsen, C. Glenn Begley, and David J. Izon Blood 2007 110: 3753-3762. Prepublished online August 13, 2007; DOI 10.1182/blood-2006-12-063644 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   PHAGOCYTES: Histone H2B as a functionally important plasminogen receptor on macrophages Riku Das, Tim Burke, and Edward F. Plow Blood 2007 110: 3763-3772. Prepublished online August 9, 2007; DOI 10.1182/blood-2007-03-079392 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Gi2 is required for chemokine-induced neutrophil arrest Alexander Zarbock, Tracy L. Deem, Tracy L. Burcin, and Klaus Ley Blood 2007 110: 3773-3779. Prepublished online August 15, 2007; DOI 10.1182/blood-2007-06-094565 [Abstract] [Full Text] [PDF]   RED CELLS: Brief report  Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations Ivana De Domenico, Michael B. Vaughn, Donghoon Yoon, James P. Kushner, Diane M. Ward, and Jerry Kaplan Blood 2007 110: 3780-3783. Prepublished online August 28, 2007; DOI 10.1182/blood-2007-07-100248 [Abstract] [Full Text] [PDF]   TRANSPLANTATION: Late mortality after allogeneic hematopoietic cell transplantation and functional status of long-term survivors: report from the Bone Marrow Transplant Survivor Study Smita Bhatia, Liton Francisco, Andrea Carter, Can-Lan Sun, K. Scott Baker, James G. Gurney, Philip B. McGlave, Auayporn Nademanee, Margaret O'Donnell, Norma K. C. Ramsay, Leslie L. Robison, David Snyder, Anthony Stein, Stephen J. Forman, and Daniel J. Weisdorf Blood 2007 110: 3784-3792. Prepublished online August 1, 2007; DOI 10.1182/blood-2007-03-082933 [Abstract] [Full Text] [PDF]   Regulatory dendritic cells protect against cutaneous chronic graft-versus-host disease mediated through CD4+CD25+Foxp3+ regulatory T cells Shigeharu Fujita, Yumiko Sato, Kaori Sato, Kawori Eizumi, Tomohiro Fukaya, Masato Kubo, Naohide Yamashita, and Katsuaki Sato Blood 2007 110: 3793-3803. Prepublished online August 8, 2007; DOI 10.1182/blood-2007-04-086470 [Abstract] [Full Text] [PDF]   Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease Xiao Chen, Sanja Vodanovic-Jankovic, Bryon Johnson, Melissa Keller, Richard Komorowski, and William R. Drobyski Blood 2007 110: 3804-3813. Prepublished online August 10, 2007; DOI 10.1182/blood-2007-05-091074 [Abstract] [Full Text] [PDF] [Supplemental Figure]   CORRESPONDENCE: Lenalidomide-induced severe hepatotoxicity Subuhee Hussain, Royston Browne, Julie Chen, and Samir Parekh Blood 2007 110: 3814. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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