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Tec protein-tyrosine kinase is involved in interleukin-3 signaling pathway
H Mano, Y Yamashita, K Sato, Y Yazaki and H Hirai
Department of Molecular Biology, Jichi Medical School, Tochigiken, Japan.
Among cytoplasmic protein-tyrosine kinases (PTKs) Tec now forms a novel
subfamily with recently identified Tec-related PTKs (Btk and Itk/Tsk). Tec
is known to be abundantly expressed in myeloid cells, and multiple forms of
Tec protein can be generated via the mechanism of alternative splicing. In
this report, we have investigated 5'-terminal diversity of the tec messages
to demonstrate a predominant form of the Tec protein in mouse hematopoietic
cell lines. Using anti-Tec serum, we could show that stimulation with
interleukin-3 (IL-3) can induce tyrosine phosphorylation of Tec both in
myeloid and pro-B-cell lines. IL-3 stimulation was also shown to induce
kinase activity of Tec. Furthermore, we could demonstrate that Tec is
constitutively associated with the Shc protein in vivo. Thus, we conclude
that Tec is involved in the signaling pathway of IL-3.
Volume 85,
Issue 2,
pp. 343-350,
01/15/1995
Copyright © 1995 by The American Society of Hematology
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276(42):
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|
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|
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|
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|
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|
|
|
|
|
|
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272(43):
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|
|
|
|
|
|
|
M. Fukuda, T. Kojima, H. Kabayama, and K. Mikoshiba
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271(48):
30303 - 30306.
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[Full Text]
[PDF]
|
|
|
|
|
|
|
T Hara and A Miyajima
Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis
Stem Cells,
November 1, 1996;
14(6):
605 - 618.
[Abstract]
|
|
|
|
|
|
|
N. Jiang, T.-C. He, A. Miyajima, and D. M. Wojchowski
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J. Biol. Chem.,
July 12, 1996;
271(28):
16472 - 16476.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W. Yang, S. N. Malek, and S. Desiderio
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J. Biol. Chem.,
September 1, 1995;
270(35):
20832 - 20840.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Odai, K. Sasaki, A. Iwamatsu, Y. Hanazono, T. Tanaka, K. Mitani, Y. Yazaki, and H. Hirai
The Proto-oncogene Product c-Cbl Becomes Tyrosine Phosphorylated by Stimulation with GM-CSF or Epo and Constitutively Binds to the SH3 Domain of Grb2/Ash in Human Hematopoietic Cells
J. Biol. Chem.,
May 5, 1995;
270(18):
10800 - 10805.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T Taniguchi
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Science,
April 14, 1995;
268(5208):
251 - 255.
[Abstract]
[PDF]
|
|
|
|
|
|
|
H.-Y. Jui, R.-J. Tseng, X. Wen, H.-I Fang, L.-M. Huang, K.-Y. Chen, H.-J. Kung, D. K. Ann, and H.-M. Shih
Protein-tyrosine Phosphatase D1, a Potential Regulator and Effector for Tec Family Kinases
J. Biol. Chem.,
December 22, 2000;
275(52):
41124 - 41132.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. L. Craddock, J. Hobbs, C. E. Edmead, and M. J. Welham
Phosphoinositide 3-Kinase-dependent Regulation of Interleukin-3-induced Proliferation. INVOLVEMENT OF MITOGEN-ACTIVATED PROTEIN KINASES, SHP2 AND Gab2
J. Biol. Chem.,
June 22, 2001;
276(26):
24274 - 24283.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Yoshida, Y. Yamashita, A. Miyazato, K.-i. Ohya, A. Kitanaka, U. Ikeda, K. Shimada, T. Yamanaka, K. Ozawa, and H. Mano
Mediation by the Protein-tyrosine Kinase Tec of Signaling between the B Cell Antigen Receptor and Dok-1
J. Biol. Chem.,
August 4, 2000;
275(32):
24945 - 24952.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
