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1 Department of Pediatrics, Beth Israel Hospital, and the Department of
Pediatrics, Harvard Medical School, Boston, Mass.
1. The mechanical fragilities of incubated and nonincubated erythrocytes of
normal newborn infants, children and adults have been determined through the
use of a simplified rotator. 2. The mean mechanical fragility of nonincubated erythrocytes was 7.1 per
cent for newborns, 4.0 per cent for children and adults; the mean mechanical
fragility of incubated erythrocytes was 13.4 per cent for newborns, 10.5 per cent
for children and 10.8 per cent for adults. 3. The possible relationship of increased mechanical fragility of erythrocytes
in the newborn to increased hemolysis in the neonatal period is suggested. 4. Possible causes of variation in the determination of mechanical fragility
of incubated erythrocytes are discussed.
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| Copyright © 1953 by American Society of Hematology Online ISSN: 1528-0020 | |||||||||
