|
|
 Previous Article | Table of Contents | Next Article 
GMP-140 mediates adhesion of stimulated platelets to neutrophils
SA Hamburger and RP McEver
St Francis Medical Research Institute, Oklahoma City, OK.
In vivo, platelets associate with neutrophils at sites of hemorrhage or
inflammation. In vitro, stimulated platelets bind to neutrophils in a
Ca2(+)-dependent manner. GMP-140, an integral membrane glycoprotein found
in secretory granules of platelets and endothelium, is rapidly translocated
to the cell surface after cellular activation. It shares sequence
similarity with two leukocyte adhesion molecules, ELAM-1 and a lymphocyte
homing receptor. We have recently shown that neutrophils bind to purified
GMP-140 in a Ca2(+)-dependent fashion, and that GMP- 140 participates in
adhesion of neutrophils to activated endothelium. In this study we
demonstrate that GMP-140 also mediates adhesion of neutrophils to
stimulated platelets. Fixed thrombin-activated human platelets, but not
unstimulated platelets, formed rosettes around neutrophils in the presence
of Ca2+. The binding of platelets to neutrophils was inhibited by a
monoclonal antibody to GMP-140 and by purified GMP-140. By promoting close
cell-cell contact, GMP-140 may recruit both platelets and neutrophils to
sites of tissue injury as well as modulate the function of each cell type
by the other.
Volume 75,
Issue 3,
pp. 550-554,
02/01/1990
Copyright © 1990 by The American Society of Hematology
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati What's this?
This article has been cited by other articles:
|
|
|
|
 
D. Aradi, A. Konyi, L. Palinkas, T. Berki, T. Pinter, T. Tahin, I. Horvath, L. Papp, and A. Komocsi
Thienopyridine Therapy Influences Late Outcome After Coronary Stent Implantation
Angiology,
May 1, 2008;
59(2):
172 - 178.
[Abstract]
[PDF]
|
|
|
|
|
|
|
X. Tu, X. Chen, Y. Xie, S. Shi, J. Wang, Y. Chen, and J. Li
Anti-inflammatory Renoprotective Effect of Clopidogrel and Irbesartan in Chronic Renal Injury
J. Am. Soc. Nephrol.,
January 1, 2008;
19(1):
77 - 83.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
I. Goubareva, E. Gkaliagkousi, A. Shah, L. Queen, J. Ritter, and A. Ferro
Age decreases nitric oxide synthesis and responsiveness in human platelets and increases formation of monocyte-platelet aggregates
Cardiovasc Res,
September 1, 2007;
75(4):
793 - 802.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. O'Kennedy, L. Crosbie, M. van Lieshout, J. I Broom, D. J Webb, and A. K Duttaroy
Effects of antiplatelet components of tomato extract on platelet function in vitro and ex vivo: a time-course cannulation study in healthy humans.
Am. J. Clinical Nutrition,
September 1, 2006;
84(3):
570 - 579.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Ferenc and F.-J. Neumann
Efficacy of primary PCI: the microvessel perspective
Eur. Heart J. Suppl.,
October 1, 2005;
7(suppl_I):
I4 - I9.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Murohara, H. Ikeda, Y. Otsuka, M. Aoki, N. Haramaki, A. Katoh, Y. Takajo, and T. Imaizumi
Inhibition of Platelet Adherence to Mononuclear Cells by {alpha}-Tocopherol: Role of P-Selectin
Circulation,
July 13, 2004;
110(2):
141 - 148.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H.-K. Yip, S.-S. Chen, J. S. Liu, H.-W. Chang, Y.-F. Kao, M.-Y. Lan, Y.-Y. Chang, S.-L. Lai, W.-H. Chen, and M.-C. Chen
Serial Changes in Platelet Activation in Patients After Ischemic Stroke: Role of Pharmacodynamic Modulation
Stroke,
July 1, 2004;
35(7):
1683 - 1687.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. Tchernychev, B. Furie, and B. C. Furie
Peritoneal macrophages express both P-selectin and PSGL-1
J. Cell Biol.,
December 8, 2003;
163(5):
1145 - 1155.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. D. Blann, S. K. Nadar, and G. Y.H. Lip
The adhesion molecule P-selectin and cardiovascular disease
Eur. Heart J.,
December 2, 2003;
24(24):
2166 - 2179.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Koyama, T. Maeno, S. Fukumoto, T. Shoji, T. Yamane, H. Yokoyama, M. Emoto, T. Shoji, H. Tahara, M. Inaba, et al.
Platelet P-Selectin Expression Is Associated With Atherosclerotic Wall Thickness in Carotid Artery in Humans
Circulation,
August 5, 2003;
108(5):
524 - 529.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Wahba and V. Videm
Heart surgery with extracorporeal circulation leads to platelet activation at the time of hospital discharge
Eur. J. Cardiothorac. Surg.,
June 1, 2003;
23(6):
1046 - 1050.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. P. Inwald, A. McDowall, M. J. Peters, R. E. Callard, and N. J. Klein
CD40 Is Constitutively Expressed on Platelets and Provides a Novel Mechanism for Platelet Activation
Circ. Res.,
May 16, 2003;
92(9):
1041 - 1048.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Massaguer, S. Perez-del-Pulgar, P. Engel, J. Serratosa, J. Bosch, and P. Pizcueta
Concanavalin-A-induced liver injury is severely impaired in mice deficient in P-selectin
J. Leukoc. Biol.,
August 1, 2002;
72(2):
262 - 270.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Hilf, H. Singh-Jasuja, P. Schwarzmaier, C. Gouttefangeas, H.-G. Rammensee, and H. Schild
Human platelets express heat shock protein receptors and regulate dendritic cell maturation
Blood,
May 15, 2002;
99(10):
3676 - 3682.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. I. Furman, M. R. Barnard, L. A. Krueger, M. L. Fox, E. A. Shilale, D. M. Lessard, P. Marchese, A. L. Frelinger III, R. J. Goldberg, and A. D. Michelson
Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction
J. Am. Coll. Cardiol.,
October 1, 2001;
38(4):
1002 - 1006.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Kamath, A.D. Blann, and G.Y.H. Lip
Platelet activation: assessment and quantification
Eur. Heart J.,
September 1, 2001;
22(17):
1561 - 1571.
[PDF]
|
|
|
|
|
|
|
J.-F. Theoret, J.-G. Bienvenu, A. Kumar, and Y. Merhi
P-Selectin Antagonism with Recombinant P-Selectin Glycoprotein Ligand-1 (rPSGL-Ig) Inhibits Circulating Activated Platelet Binding to Neutrophils Induced by Damaged Arterial Surfaces
J. Pharmacol. Exp. Ther.,
August 1, 2001;
298(2):
658 - 664.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Fung, P. G. Loubser, A. Undar, M. Mueller, C. Sun, W. N. Sun, W. K. Vaughn, and C. D. Fraser Jr
Inhibition of complement, neutrophil, and platelet activation by an anti-factor D monoclonal antibody in simulated cardiopulmonary bypass circuits
J. Thorac. Cardiovasc. Surg.,
July 1, 2001;
122(1):
113 - 122.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J.-G. Bienvenu, J.-F. Tanguay, J.-F. Theoret, A. Kumar, R. G. Schaub, and Y. Merhi
Recombinant Soluble P-Selectin Glycoprotein Ligand-1-Ig Reduces Restenosis Through Inhibition of Platelet-Neutrophil Adhesion After Double Angioplasty in Swine
Circulation,
February 27, 2001;
103(8):
1128 - 1134.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. J. Eppihimer and R. G. Schaub
P-Selectin-Dependent Inhibition of Thrombosis During Venous Stasis
Arterioscler. Thromb. Vasc. Biol.,
November 1, 2000;
20(11):
2483 - 2488.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. I. Simon, Z. Chen, H. Xu, C. Q. Li, J.-f. Dong, L. V. McIntire, C. M. Ballantyne, L. Zhang, M. I. Furman, M. C. Berndt, et al.
Platelet Glycoprotein Ib{alpha} Is a Counterreceptor for the Leukocyte Integrin Mac-1 (CD11b/CD18)
J. Exp. Med.,
July 10, 2000;
192(2):
193 - 204.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. W. Schmidtke and S. L. Diamond
Direct Observation of Membrane Tethers Formed during Neutrophil Attachment to Platelets or P-selectin under Physiological Flow
J. Cell Biol.,
May 1, 2000;
149(3):
719 - 730.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. A. KIRSCHENBAUM, M. AZIZ, M. E. ASTIZ, D. C. SAHA, and E. C. RACKOW
Influence of Rheologic Changes and Platelet-Neutrophil Interactions on Cell Filtration in Sepsis
Am. J. Respir. Crit. Care Med.,
May 1, 2000;
161(5):
1602 - 1607.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
S. B. Forlow, R. P. McEver, and M. U. Nollert
Leukocyte-leukocyte interactions mediated by platelet microparticles under flow
Blood,
February 15, 2000;
95(4):
1317 - 1323.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F.-J. Neumann, D. Zohlnhofer, L. Fakhoury, I. Ott, M. Gawaz, and A. Schomig
Effect of glycoprotein IIb/IIIa receptor blockade on platelet-leukocyte interaction and surface expression of the leukocyte integrin Mac-1 in acute myocardial infarction
J. Am. Coll. Cardiol.,
November 1, 1999;
34(5):
1420 - 1426.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. S. Rinder, H. M. Rinder, M. J. Smith, J. B. Tracey, J. Fitch, L. Li, S. A. Rollins, and B. R. Smith
SELECTIVE BLOCKADE OF MEMBRANE ATTACK COMPLEX FORMATION DURING SIMULATED EXTRACORPOREAL CIRCULATION INHIBITS PLATELET BUT NOT LEUKOCYTE ACTIVATION
J. Thorac. Cardiovasc. Surg.,
September 1, 1999;
118(3):
460 - 466.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W. Reents, J. Babin-Ebell, M. R. Misoph, A. Schwarzkopf, and O. Elert
Influence of different autotransfusion devices on the quality of salvaged blood
Ann. Thorac. Surg.,
July 1, 1999;
68(1):
58 - 62.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Bombeli, B. R. Schwartz, and J. M. Harlan
Endothelial Cells Undergoing Apoptosis Become Proadhesive for Nonactivated Platelets
Blood,
June 1, 1999;
93(11):
3831 - 3838.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Kumar, M. P. Villani, U. K. Patel, J. C. Keith Jr, and R. G. Schaub
Recombinant Soluble Form of PSGL-1 Accelerates Thrombolysis and Prevents Reocclusion in a Porcine Model
Circulation,
March 16, 1999;
99(10):
1363 - 1369.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Merhi, P. Provost, P. Chauvet, J.-F. Theoret, M. L. Phillips, and J.-G. Latour
Selectin Blockade Reduces Neutrophil Interaction With Platelets at the Site of Deep Arterial Injury by Angioplasty in Pigs
Arterioscler. Thromb. Vasc. Biol.,
February 1, 1999;
19(2):
372 - 377.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Pabla, A. S. Weyrich, D. A. Dixon, P. F. Bray, T. M. McIntyre, S. M. Prescott, and G. A. Zimmerman
Integrin-dependent Control of Translation: Engagement of Integrin alpha IIbbeta 3 Regulates Synthesis of Proteins in Activated Human Platelets
J. Cell Biol.,
January 11, 1999;
144(1):
175 - 184.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. W. Hartwell, T. N. Mayadas, G. Berger, P. S. Frenette, H. Rayburn, R. O. Hynes, and D. D. Wagner
Role of P-Selectin Cytoplasmic Domain in Granular Targeting In Vivo and in Early Inflammatory Responses
J. Cell Biol.,
November 16, 1998;
143(4):
1129 - 1141.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. D. Blagoveshchenskaya, E. W. Hewitt, and D. F. Cutler
A Balance of Opposing Signals within the Cytoplasmic Tail Controls the Lysosomal Targeting of P-selectin
J. Biol. Chem.,
October 23, 1998;
273(43):
27896 - 27903.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Aoki and H. Tomoda
Plasma Soluble P-Selectin in Acute Myocardial Infarction: Effects of Coronary Recanalization Therapy
Angiology,
September 1, 1998;
49(9):
807 - 813.
[Abstract]
[PDF]
|
|
|
|
|
|
|
K. Konstantopoulos, S. Neelamegham, A. R. Burns, E. Hentzen, G. S. Kansas, K. R. Snapp, E. L. Berg, J. D. Hellums, C. W. Smith, L. V. McIntire, et al.
Venous Levels of Shear Support Neutrophil-Platelet Adhesion and Neutrophil Aggregation in Blood via P-Selectin and ß2-Integrin
Circulation,
September 1, 1998;
98(9):
873 - 882.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
F. Tacchini-Cottier, C. Vesin, M. Redard, W. Buurman, and P. F. Piguet
Role of TNFR1 and TNFR2 in TNF-Induced Platelet Consumption in Mice
J. Immunol.,
June 15, 1998;
160(12):
6182 - 6186.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Pan, L. Xia, and R. P. McEver
Comparison of Promoters for the Murine and Human P-selectin Genes Suggests Species-specific and Conserved Mechanisms for Transcriptional Regulation in Endothelial Cells
J. Biol. Chem.,
April 17, 1998;
273(16):
10058 - 10067.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Ostrovsky, A. J. King, S. Bond, D. Mitchell, D. E. Lorant, G. A. Zimmerman, R. Larsen, X. F. Niu, and P. Kubes
A Juxtacrine Mechanism for Neutrophil Adhesion on Platelets Involves Platelet-Activating Factor and a Selectin-Dependent Activation Process
Blood,
April 15, 1998;
91(8):
3028 - 3036.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Xia, J. Pan, L. Yao, and R. P. McEver
A Proteasome Inhibitor, an Antioxidant, or a Salicylate, but not a Glucocorticoid, Blocks Constitutive and Cytokine-Inducible Expression of P-Selectin in Human Endothelial Cells
Blood,
March 1, 1998;
91(5):
1625 - 1632.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Bombeli, B. R. Schwartz, and J. M. Harlan
Adhesion of Activated Platelets to Endothelial Cells: Evidence for a GPIIbIIIa-dependent Bridging Mechanism and Novel Roles for Endothelial Intercellular Adhesion Molecule 1 (ICAM-1), alpha vbeta 3 Integrin, and GPIbalpha
J. Exp. Med.,
February 2, 1998;
187(3):
329 - 339.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. D. Blagoveshchenskaya, J. P. Norcott, and D. F. Cutler
Lysosomal Targeting of P-selectin Is Mediated by a Novel Sequence within Its Cytoplasmic Tail
J. Biol. Chem.,
January 30, 1998;
273(5):
2729 - 2737.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. K. Brown, P. M. Henson, J. Maclouf, M. Moyle, J. A. Ely, and G. Scott Worthen
Neutrophil-Platelet Adhesion: Relative Roles of Platelet P-Selectin and Neutrophil beta 2 (CD18) Integrins
Am. J. Respir. Cell Mol. Biol.,
January 1, 1998;
18(1):
100 - 110.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
J. Joseph, P. Harrison, I. Mackie, and S.J. Machin
Review : Platelet activation markers and the primary antiphospholipid syndrome (PAPS)
Lupus,
January 1, 1998;
7(2_suppl):
S48 - S51.
[Abstract]
[PDF]
|
|
|
|
|
|
|
A. Kumar, J. L. Hoover, C. A. Simmons, V. Lindner, and R. J. Shebuski
Remodeling and Neointimal Formation in the Carotid Artery of Normal and P-Selectin–Deficient Mice
Circulation,
| |
