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Chemotherapy v marrow transplantation for adults with acute nonlymphocytic
leukemia: a five-year follow-up
FR Appelbaum, LD Fisher and ED Thomas
Fred Hutchinson Cancer Research Center, Seattle, WA 98104.
We previously published the results of a prospective comparison of
continued chemotherapy or marrow transplantation for adults with acute
nonlymphocytic leukemia (ANL) who had achieved a first remission. This
report updates that study now that greater than 5 years have passed since
the last patient was entered. Among 86 patients eligible for comparison, 43
had no donors and were treated with continued chemotherapy, 43 had donors,
but 10 declined transplantation and 33 were transplanted. Five-year
disease-free survivals are 21% for the chemotherapy group, 48% for the
transplant group, and 10% for the group with matched siblings who declined
transplantation.
Volume 72,
Issue 1,
pp. 179-184,
07/01/1988
Copyright © 1988 by The American Society of Hematology
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