Blood, 1952, Vol. 7, No. 5, pp. 545-549.
© 1952 American Society of Hematology, Inc.
Report of 193 Marrow Biopsy Specimens Cultured
for Histoplasma Capsulatum
STEVEN O. SCHWARTZ M.D.1,
SIDNEY BARSKY M.D.1,
CARRIE WOOLSEY 1, and
HELEN L. GANT 1
1 Hematology Laboratory and the Hektoen Institute for Medical Research of
the Cook County Hospital, Chicago, Illinois.
One hundred ninety-three cultures of marrows were studied for the presence
of fungi.
Many of the cases studied had one or more of the classical conditions of
histoplasmosis, such as anemia, leukopenia, splenomegaly, hepatomegaly, irregular elevations in temperature, pulmonary disease, and generalized lymphadenopathy.
Histoplasma capsulatum was found in only one case.
Considering the high incidence of histoplasmin reactors in this locality, it
appears that routine cultures of the marrow for Histoplasma capsulatum have
little value in histoplasmosis case findings.
Submitted on November 23, 1951
Accepted on February 8, 1952