Blood, 1960, Vol. 16, No. 6, pp. 1762-1769.
© 1960 American Society of Hematology, Inc.
The Effect of Homologous Marrow Transplantation
on the Survival of Monkeys Following
Sublethal Who1e-Body Radiation
FRANCES E. NEWSOME 1 and
R. R. OVERMAN 1
1 Clinical Physiological Laboratories of the Institute of Clinical Investigation,
University of Tennessee College of Medicine, Memphis. Tenn.
Homologous bone marrow given to the rhesus monkey 30 hours after LD 10
radiation dose of 550r increased the mortality rate expected from the radiation
alone. The symptoms produced resembled those obtained at higher doses of
radiation. The effects of marrow given 48 hours after radiation differed little
from those produced by the radiation alone. It is suggested that the 30-hour
injection elicited a more violent reaction or that the reaction occurred during
a more decisive time in the process of recovery.
Submitted on July 1, 1960
Accepted on August 25, 1960
