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The history of a family with three cases of neonatal neutropenia is reported.
During the mothers last pregnancy leukocyte antibody titers were found to
be rising, culminating in a titer of 1:512 at delivery, when leukolysins and
passive transfer of antibody to the fetus in the cord blood were also demonstrated. This pregnancy resulted in an infant with a severe degree of neutropenia during its neonatal period. The original sensitization was attributed to
prior transfusion with the husbands whole fresh blood. The whole process
can be compared with the sensitization produced by the Rh factors.
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| Copyright © 1960 by American Society of Hematology Online ISSN: 1528-0020 | |||||||||