Blood, 1960, Vol. 16, No. 6, pp. 1736-1744.
© 1960 American Society of Hematology, Inc.
High Fetal—Hemoglobin C Disease: A New Syndrome
WILLIAM F. MCCORMICK 1 and
ELEANOR W. HUMPHREYS 1
1 Division of Pathology and Microbiology, University of Tennessee, and the
City of Memphis Hospitals, Memphis, Tennessee.
A case of interaction of the genes for hemoglobin C and "high fetal" has
been reported, with an incomplete family study. The "high F" gene seems to
behave as a dominant one.
A discussion of the relationship, if any, with this disease to "classical" C-thalassemia was presented. The evidence is inconclusive, but this case does
not fit the picture of C-thalassemia as previously reported and is considered to
be a separate condition.
Submitted on April 18, 1960
Accepted on September 7, 1960
