Blood, 1960, Vol. 16, No. 3, pp. 1307-1312.
© 1960 American Society of Hematology, Inc.
Electron Microscopic Localization of Russell
Bodies in the Human Plasma Cell
RONALD A. WELSH 1
1 Department of Pathology, Louisiana State University School of Medicine,
New Orleans, La.
The location of Russell bodies in the human plasma cell was shown by
electron microscopy to be within the intracisternal space of the endoplasmic
reticulum. The significance of this finding was discussed from the standpoint
of possible intracellular function of the endoplasmic reticulum. The appearance of the affected plasma cells tended to negate a degenerative process,
and the suggestion was offered that the Russell body results from a condensation of intracisternal secretion.
Submitted on January 11, 1960
Accepted on April 13, 1960
