Blood, 1960, Vol. 16, No. 3, pp. 1279-1284.
© 1960 American Society of Hematology, Inc.
Febrile Response to Bacterial Pyrogens in Leukemia
ABRAHAM I. BRAUDE 1,
JAY BECK 1, and
MARGARET ZALESKY 1
1 Department of Internal Medicine, Southwestern Medical School, University
of Texas, Dallas, Tex., and the Department of Medicine, University of Pittsburgh School
of Medicine, Pittsburgh, Pa.
1. The intravenous injection of 50,000,000 dead typhoid-paratyphoid bacilli
produced a greater febrile reaction in nonbeukemics than in patients with
chronic lymphocytic leukemia.
2. These results suggest that granulocytes may contribute to the production
of the fever that follows injection of bacterial pyrogens.
Submitted on July 12, 1959
Accepted on February 18, 1960
