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Blood, 1960, Vol. 15, No. 6, pp. 901-908.
© 1960 American Society of Hematology, Inc.


Brief Note: A Variety of Human Hemoglobin with 4 Distinct Electrophoretic Components

JEAN ATWATER 1, I. ROBERT SCHWARTZ 1, and L. M. TOCANTINS 1

1 Hematology-Obstetrical Clinic of the Jefferson Medical College Hospital and the Charlotte Drake Cardeza Foundation, Jefferson Medical College, Philadelphia, Pa.

A human hemoglobin with four distinct electrophoretic components was observed in an individual with leptocytosis and reticulocytosis. Three of the components were the previously reported hemoglobins A, C and G. The fourth (Porter) with a mobility of zero on conventional paper electrophoresis in alkaline buffer of pH 8.6, appears to be a new component arising as a result of the random association of the other two abnormal components.

Submitted on December 17, 1959
Accepted on March 24, 1960


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