Blood, 1960, Vol. 15, No. 6, pp. 901-908.
© 1960 American Society of Hematology, Inc.
Brief Note: A Variety of Human Hemoglobin with 4 Distinct
Electrophoretic Components
JEAN ATWATER 1,
I. ROBERT SCHWARTZ 1, and
L. M. TOCANTINS 1
1 Hematology-Obstetrical Clinic of the Jefferson Medical College Hospital and
the Charlotte Drake Cardeza Foundation, Jefferson Medical College, Philadelphia, Pa.
A human hemoglobin with four distinct electrophoretic components was
observed in an individual with leptocytosis and reticulocytosis. Three of the
components were the previously reported hemoglobins A, C and G. The fourth
(Porter) with a mobility of zero on conventional paper electrophoresis in
alkaline buffer of pH 8.6, appears to be a new component arising as a result
of the random association of the other two abnormal components.
Submitted on December 17, 1959
Accepted on March 24, 1960