Blood, 1960, Vol. 15, No. 5, pp. 690-697.
© 1960 American Society of Hematology, Inc.
Analysis of Fibrinolysis by the Use of Epsilon-Aminocaproic
Acid: Preliminary Report
KATSUHIRO FUKUTAKE 1,
KEIJI SHIDA 1,
TOYOME ARAKAWA 1, and
KATSUJI KATO 1
1 Department IInd Physiology (Hematology), Tokyo Medical College Hospital,
Tokyo, Japan.
From the foregoing analysis of the inhibitory action of 
-aminocaproic acid
in the fibrinolytic process, it is evident that the process involves two reaction
phases, fibrinolysis and metafibrinolysis.
Fibrinolysopeptide and metafibrin are split off from fibrin in fibrinolysis.
The former is a peptide with N-terminal glycine, while the latter is a monochloracetic acid-soluble metaprotein having both aspartic acid and tyrosine
as N-terminal amino acids.
