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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by FIRKIN, B. G. Articles by HARRINGTON, W. J. Search for Related Content PubMed PubMed Citation Articles by FIRKIN, B. G. Articles by HARRINGTON, W. J. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1960, Vol. 15, No. 3, pp. 388-394. © 1960 American Society of Hematology, Inc. A Method for Evaluating the Hemostatic Effect of Various Agents in Thrombocytopenic Rats and Mice B. G. FIRKIN 1, GRACE ARIMURA 1, and W. J. HARRINGTON 1 1 Washington University School of Medicine, St. Louis, Mo. A simple method for measuring the control of blood loss in thrombocytopenic rats and mice is described. The administration of lyophilized platelets, brain phospholipid extract and soya bean extract failed to correct the blood loss in the thrombocytopenic animal. The results obtained with this method have failed to support the effectiveness of "platelet substitutes" in in vivo systems and reaffirm the requisites of viability and recirculation for platelet transfusions. Submitted on June 5, 1959 Accepted on August 5, 1959 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: A. P. Bode, R. M. Lust, M. S. Read, and T. H. Fischer Correction of the Bleeding Time With Lyophilized Platelet Infusions in Dogs on Cardiopulmonary Bypass Clinical and Applied Thrombosis/Hemostasis, January 1, 2008; 14(1): 38 - 54. [Abstract] [PDF]

	Copyright © 1960 by American Society of Hematology         Online ISSN: 1528-0020