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Next Article 
Blood, 1960, Vol. 15, No. 3, pp. 313-331.
© 1960 American Society of Hematology, Inc.
Leukemia in Hiroshima Atomic Bomb Survivors
ROBERT HEYSSEL 1,
A. BERTRAND BRILL 1,
LOWELL A. WOODBURY 1,
EDWIN T. NISHIMURA 1,
TARUNENDU GHOSE 1,
TAKASHI HOSHINO 1, and
MITSURU YAMASAKI 1
1 Atomic Bomb Casualty Commission, Hiroshima-Nagasaki, Japan
The incidence of leukemia is higher among those closely exposed than
among those more remote from the hypocenter. This increase was first manifest
approximately three years following exposure. It apparently reached its peak
between the years 1950 and 1952. Thereafter, the incidence has been diminishing, but 13 years after exposure it is still higher than would be expected in the
general population. The type of leukemia most increased in incidence is the
chronic granulocytic variety. No apparent difference in the natural history of
the specific types of leukemia in exposed and nonexposed Japanese has been
observed. Preliminary analyses of the data show a linear relation between
dose of radiation and incidence of leukemia above 50 to 100 rad. Below this
dose, the shape of the curve is not certain.
Submitted on June 8, 1959
Accepted on August 12, 1959
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