Blood, 1960, Vol. 15, No. 1, pp. 30-35.
© 1960 American Society of Hematology, Inc.
Iron Enzymes in Iron Deficiency. V.
Succinic Dehydrogenase in Rat Liver,
Kidney and Heart
ERNEST BEUTLER 1 and
RICHARD K. BLAISDELL 1
1 Argonne Cancer Research Hospital, operated by The University of Chicago
for the U. S. Atomic Energy Commission, and the Department of Medicine, The University
of Chicago, Chicago, Ill.
Manometric determinations of the enzyme succinic dehydrogenase have
been carried out on liver, heart and kidneys of iron-deficient and control rats.
Even after prolonged, moderately severe iron deficiency, no decrease in
enzyme activity of liver homogenates could be demonstrated. However,
enzyme depletion could be demonstrated to have occurred in the hearts
and kidneys of iron-deficient animals.
Submitted on February 24, 1959
Accepted on March 31, 1959
