Blood, 1960, Vol. 15, No. 1, pp. 186-191.
© 1960 American Society of Hematology, Inc.
The Duffy Blood Group System in Transfusion
Reactions: A Review of the Literature and
Report of Four Cases
ALLAN COMPTON 1 and
JANE M. HABER 1
1 Blood Bank of The New York Hospital-Cornell Medical Center, New York,
N. Y.
1. The literature on the incidence and inheritance of the "Duffy" blood
group factors and their significance in blood transfusion and erythroblastosis
fetalis is briefly reviewed.
2. Four new cases in which anti-Fya was detected are reported.
3. The necessity for the use of the Coombs’ compatibility test with a
potent Coombs’ serum to prevent reactions due to anti-Fya is re-emphasized.
4. The inadequacy of a 15 minute incubation period for the Coombs’ compatibility test in certain cases is noted.
5. The desirability of specific identification of an antibody detected in
a patient’s serum prior to transfusion whenever possible is suggested.
Submitted on January 31, 1959
Accepted on March 18, 1959
