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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by YAKAITIS, A. A. Search for Related Content PubMed PubMed Citation Articles by YAKAITIS, A. A. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1959, Vol. 14, No. 9, pp. 1033-1039. © 1959 American Society of Hematology, Inc. The Relationship of Age, Strain and Species to the Reducing Activity of Leukocytes ALBINA ANN YAKAITIS 1 1 Detroit Institute of Cancer Research, Detroit, Mich. A method is presented for studying the reducing activity of leukocytes of mice and rats using 2-(p-iodophenyl)-3-)p-nitrophenyl)-5-phenyltetrazolium chloride (INT). Between 48.0 per cent and 83.8 per cent of the leukocytes of young adult mice and between 47.8 per cent and 68.0 per cent of the leukocytes of young rats showed formazan formation. Infant mice of C3Hf and BALBf strains had appreciably fewer leukocytes with the ability to reduce tetrazolium than did young adults of their respective strains. Healthy adult mice belonging to the leukemia susceptible AKR strain showed a relatively high degree of leukocytic reduction. Old mice of the C3Hfstrain showed less formazan formation than young adult animals. This decrease was more marked for the male members of the species. Submitted on October 15, 1958 Accepted on January 12, 1959 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1959 by American Society of Hematology         Online ISSN: 1528-0020