Blood, 1959, Vol. 14, No. 5, pp. 558-563.
© 1959 American Society of Hematology, Inc.
The Proportion of Reticulocytes in the Erythrocytes of the
Spleen as Compared with Those of Circulating Blood,
with Special Reference to Hemolytic States
MARGRET BERENDES 1
1 Department of Medicine, University of Minnesota Hospitals, Minneapolis,
Minn.
1. Comparative studies of reticulocyte percentages have been made on the
spleens of normal dogs, dogs with phenylhydrazine hemolytic disease, and
human cases of hemolytic jaundice. Splenic artery and vein blood has been
compared in some of these, both before and after adrenalin.
2. No significant differences were found, as between peripheral, splenic
arterial and venous blood, with or without the use of adrenalin.
3. Imprint and "squeeze" preparations of splenic parenchyma consistently
gave higher percentages ranging from 1.5 to 3.5 times the peripheral values,
the most marked differences being noted in the normal dog (11.5 to 27 x).
4. The possible significance of these findings is discussed.
Submitted on May 23, 1958
Accepted on November 1, 1958
