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Blood, 1959, Vol. 14, No. 12, pp. 1345-1349.
© 1959 American Society of Hematology, Inc.


Brief Note: The Free Amino Acid Changes in Plasma Following Coagulation and Plasminogen Activation

SAUL I. COHEN 1

1 Department of Surgery, Harvard Medical School, Boston, Mass., and the West Roxbury Veterans Administration Hospital, West Roxbury, Mass.

Arginine and lysine are liberated in human blood plasma after plasma plasminogen activation to the protease plasmin as well as after plasma recalcification and subsequent coagulation. Furthermore, digestion of fibrinogen by plasmin results in progressive release of these same amino acids.

Submitted on February 18, 1959
Accepted on April 6, 1959


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