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1 Department of Hematology, Walter Reed Army Institute of Research, Walter
Reed Army Medical Center, Washington, D. C.
The disappearance from the circulation of Heinz bodies, produced by
incubation of blood with phenylhydrazine, was studied in normal and
splenectomized rabbits. In the intact animal, red cells damaged by this
procedure are removed largely by the spleen. In both intact and splenectomized rabbits, the Heinz bodies are withdrawn from the circulation by
removal in toto of the red cells containing them.
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