Blood, 1959, Vol. 14, No. 10, pp. 1094-1102.
© 1959 American Society of Hematology, Inc.
A New Property of Iso-Agglutinins of the
ABO Blood Group System
A. RICHARDSON JONES 1 and
LORRAINE KANEB 1
1 Blood Grouping Laboratory of Boston, The Children’s Medical Center, and the
Department of Pediatrics, Harvard Medical School, Boston, Mass.
A new agglutination phenomenon in the ABO group system is described.
This phenomenon consists of the development of agglutinates by interaction
between a single specifically sensitized cell and other unsensitized, nonantigenic cells. Aggregates of cells formed in this way are tentatively described
as "anomalous mixed agglutinates."
Some of the properties of anomalous mixed agglutinates have been investigated, and the impact of these properties on the current theories of
agglutination is briefly discussed.
Submitted on November 21, 1958
Accepted on January 7, 1959
