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Blood, 1959, Vol. 14, No. 1, pp. 74-79.
© 1959 American Society of Hematology, Inc.

Multiple Hemangiomata Associated with Thrombocytopenia: Remarks on the Pathogenesis of the Thrombocytopenia in this Syndrome

ELIAHU GILON 1, BRACHA RAMOT 1, and CHAIM SHEBA 1

1 Tel-Hashomer Government Hospital, Israel.

1. A 13-year-old girl with multiple hemangiomata and thrombocytopenia is described.

2. Complications of surgical treatment included severe bleeding, septicemia and a fibrinolytic event.

3. Simultaneous platelet counts from the tumor and peripheral blood were performed and showed a significantly higher concentration of platelets in the tumor vessels.

4. With the rise in the platelet count, a decreased platelet fragility as well as a persistently abnormal prothrombin consumption could be demonstrated.

5. The possible role of the tumor in the pathogenesis of the thrombocytopenia is discussed.

Submitted on December 27, 1957
Accepted on July 14, 1958


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