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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by CALVERT, R. J. Articles by MACBEAN, A. L. Search for Related Content PubMed PubMed Citation Articles by CALVERT, R. J. Articles by MACBEAN, A. L. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1958, Vol. 13, No. 9, pp. 894-898. © 1958 American Society of Hematology, Inc. Megaloblastic Anemia from Methophenobarbital R. J. CALVERT 1, E. HURWORTH 1, and A. L. MACBEAN 1 1 Departments of Medicine and Pathology, North Middlesex Hospital, London, N.18. A 39-year-old spinster presented with a severe megaloblastic anemia after treatment of her epilepsy for eight years with the barbiturate, methophenobarbital, taken regularly and alone in therapeutic dose. This drug appears to have caused the anemia, which may have been conditioned by a folic-acid-poor diet. Hematologic remission followed the administration of folic acid, which she has since continued to take along with her previous dose of methophenobarbital. Disordered pigment metabolism, including methemalbuminemia, is reported and discussed. Submitted on January 10, 1958 Accepted on March 6, 1958 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: J. L. PENNY Megaloblastic Anemia During Anticonvulsant Drug Therapy: A Case Report and Review of the Literature Arch Intern Med, June 1, 1963; 111(6): 744 - 749. [Abstract] [PDF]

	Copyright © 1958 by American Society of Hematology         Online ISSN: 1528-0020