Blood, 1958, Vol. 13, No. 4, pp. 359-366.
© 1958 American Society of Hematology, Inc.
Sickle Cell—Thalassemia Disease in Jamaica
J. E. MACIVER 1,
L. N. WENT 1, and
E. K. CHUICKSHANK 1
1 Departments of Pathology and Medicine, University College of the West
Indies, Mona, St. Andrew, Jamaica, B. W. I.
Two cases of sickle cell—thalassemia disease are described in young women
of mixed Chinese and African parentage. On hemoglobin electrophoresis, a
complete suppression of hemoglobin A was found, giving a picture indistinguishable from that seen in sickle cell anemia. The findings in these two
cases are contrasted with those in other examples of this disease which we
have studied in Jamaica. The importance of these findings in relation to the
diagnosis of sickle cell anemia is discussed.
Submitted on June 13, 1957
Accepted on November 18, 1957
