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Blood, 1958, Vol. 13, No. 2, pp. 156-161.
© 1958 American Society of Hematology, Inc.

Hematopoietic and Nitrogen-Sparing Effect of Preparations from Hog Gastric Mucosa with High Content of Blood Group Substances

ANGELO CRESSERI 1, AURELIO CANTONE 1, FRANCO PICCININI 1, and VITTORIO CAPRARO 1

1 Biological Laboratory of the Istituto Carlo Erba per Ricerche Terapeutiche, Milano, Italy.

A mucin fraction with high content of A and H blood group substances was obtained from hog gastric mucosa. This fraction administered per os together with vitamin B12 in rats made anemic by phenylhydrazine injection shows a significant effect on the hematologic response in comparison with the animal treated with vitamin B12 alone.

The same fraction administered per os in cortisone-treated rats has also a significant nitrogen sparing action.

The possible mechanisms and relationships of the observed biologic effects are briefly discussed.

Submitted on January 15, 1957
Accepted on September 23, 1957


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