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Blood, 1958, Vol. 13, No. 11, pp. 1063-1073.
© 1958 American Society of Hematology, Inc.


Chediak’s Anomaly of Leukocytes in Malignant Lymphoma Associated with Leukemic Manifestations: Case Report with Necropsy

P. EFRATI 1 and W. JONAS 1

1 Laboratory for Blood Morphology and the Pediatric Department, Kaplan Hospital, Rehovoth, Israel.

A case of Chediak’s anomaly of leukocytes was described, the fourth reported in the literature.

The patient was an 11-month-old boy who, in addition to Chediak’s anomaly of the leukocytes, presented a leukemic blood picture.

He died five days after admission to the hospital, and necropsy revealed a malignant lymphoma.

We consider it possible that in all the reported cases there were generalized pathologic changes in the reticulohistiocytic system.

Submitted on December 3, 1957
Accepted on May 15, 1958


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