Blood online
Home About Blood Authors Subscriptions Permission Advertising Public Access contact us
 

 
Advanced
Current Issue
First Edition
Future Articles
Archives
Submit to Blood
Search
American Society of Hematology
Meeting Abstracts
Email Alerts
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Right arrow Rights and Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by RACHMILEWITZ, M.
Right arrow Articles by GROSSOWICZ, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by RACHMILEWITZ, M.
Right arrow Articles by GROSSOWICZ, N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

arrow to previous article Previous Article  |  Table of Contents  |  Next Article next article arrow

Blood, 1957, Vol. 12, No. 9, pp. 804-813.
© 1957 American Society of Hematology, Inc.

Serum Vitamin B12 in Leukemias and Malignant Lymphomas

M. RACHMILEWITZ 1, G. IZAK 1, A. HOCHMAN 1, J. ARONOVITCH 1, and N. GROSSOWICZ 1

1 Departments of Internal Medicine ‘B’ and Bacteriology, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.

High serum vitamin B12 levels were found in chronic myeloid leukemia and in acute leukemia with myeloid differentiation. Following x-ray therapy and repeated blood transfusions, a drop of serum vitamin B12 was found.

In chronic lymphatic leukemia, undifferentiated stem cell leukemia, Hodgkin’s disease, and multiple myeloma, the serum vitamin B12 concentrations were normal.

In polycythemia with marked leukocytosis the serum B12 was normal.

In myelosclerosis high B12 values may be found.

The serum vitamin B12 in chronic myeloid leukemia is in a bound form and the binding capacity for added B12 is increased.

Serum vitamin B12 determination may be of some value in differentiating various types of leukemia and other myelo-proliferative disorders.

Submitted on October 14, 1956
Accepted on February 24, 1957


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Arch Intern MedHome page
R. P. BRITT and D. P. ROSE
Pernicious Anemia With a Normal Serum Vitamin B12 Level in a Case of Chronic Granulocytic Leukemia
Arch Intern Med, January 1, 1966; 117(1): 32 - 33.
[Abstract] [PDF]


click for free articles
home about blood authors subscriptions permissions advertising public access contact us
  Copyright © 1957 by American Society of Hematology         Online ISSN: 1528-0020