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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by BONNIN, J. A. Articles by JENNER, M. M. Search for Related Content PubMed PubMed Citation Articles by BONNIN, J. A. Articles by JENNER, M. M. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1957, Vol. 12, No. 8, pp. 726-732. © 1957 American Society of Hematology, Inc. Platelet Functional Defects in Thrombocytopenic Purpura J. A. BONNIN 1 and MISS MAUREEN JENNER 1 1 Institute of Medical and Veterinary Science, Frome Road, Adelaide, South Australia. A defect in a serum thromboplastic component was found in six patients with severe thrombocytopenic purpura in addition to the platelet thromboplastic defect. The defective sera returned to normal spontaneously upon storage at -20 C. The addition of washed normal platelets during coagulation completely corrected the serum defect in the one instance in which it was possible to carry out the experiment. It was postulated that a platelet factor was primarily at fault, resulting in the lack of immediate activation of a serum thromboplastic component. The two thromboplastic defects are cumulative and are possibly dependent upon separate platelet factors. Submitted on December 4, 1956 Accepted on March 7, 1957 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1957 by American Society of Hematology         Online ISSN: 1528-0020