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1 Department of Hematology, Walter Reed Army Institute of Research, Walter
Reed Army Medical Center, Washington, D. C.
The indirect platelet count is higher than the direct count because the red
cells, which are used as a point of reference in the indirect method, are not randomly distributed beneath the coverslip. The red cells are concentrated at the
edge of the coverslip so that the true ratio of red cells to platelets cannot be
accurately established. Indirect platelet counts based on the ratio in the central
areas of the coverslip are too high.
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