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1 Children’s Hospital, the City General Hospital, and the Department of Child
Health, The University, Sheffield, England.
Two infants with absent radii are described. Both had hemorrhagic manifestations which occurred within 24 hours of birth, and from which they eventually
died. The most important hematologic feature was absence of megakaryocytes in
the bone marrow. Five cases showing a similar picture have been recorded, four as amegakaryocytic thrombocytopenia, and one as congenital leukemia. It is suggested that these cases are related on the one hand to Fanconis anemia,
and on the other to congenital leukemia.
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