Blood, 1957, Vol. 12, No. 5, pp. 469-473.
© 1957 American Society of Hematology, Inc.
Extrusion of Nuclei of Transfused Avian Erythrocytes
in the Mammalian Spleen
ELAINE F. VORHAUS 1 and
JOSEPH C. TURNER 1
1 Department of Medicine, Columbia University College of Physicians and
Surgeons, and the Presbyterian Hospital in the City of New York.
1. Duck erythrocytes have been injected intravenously into rabbits, mice,
and guinea pigs and at intervals thereafter microscopic examination of certain
organs has been made.
2. In the guinea pig spleen extrusion of the nuclei of the duck cells has been
observed with great regularity.
3. Attempts to reproduce this phenomenon in vitro have failed.
4. It is suggested that nuclear extrusion of this kind is conditioned by (a)
the species into which the cells are transfused and (b) an intact spleen.
Submitted on September 5, 1956
Accepted on October 22, 1956
