Blood, 1957, Vol. 12, No. 5, pp. 454-460.
© 1957 American Society of Hematology, Inc.
Microdrepanocytic Disease in Greece
C. CHOREMIS 1 and
L. ZANNOS 1
1 Pediatric Clinic of Athens University.
Among the 57 patients with the hematologic picture of sickle cell anemia, examination of the parents revealed that 44 were suffering from the microdrepanocytic disease and 13 from sickle cell anemia. The much more frequent occurrence
of microdrepanocytic disease was expected since the microcytemia trait appears
to be much more frequent in Greece than the sickle cell trait.
Most patients with sickle cell anemia originated from areas where the trait
has been found in a very high frequency. In contrast, the geographical distribution of patients with microdrepanocytic disease is much wider.
Submitted on June 25, 1956
Accepted on October 24, 1956
