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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by ERSLEV, A. J. Search for Related Content PubMed PubMed Citation Articles by ERSLEV, A. J. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1955, Vol. 10, No. 6, pp. 616-622. © 1955 American Society of Hematology, Inc. Erythropoietic Function in Dilution Anemia ALLAN J. ERSLEV 1 1 The Medical Service, Fort Devens, Mass. For a period of four days, four rabbits received intravenously at 12-hour intervals large amounts (25 ml./Kg.) of a 6 per cent solution of dextran. This caused a pronounced dilution anemia. However, no increase in erythropoietic activity was observed despite the reduced oxygen content of each unit of arterial blood. Since hypervolemia and dextran per se were found not to interfere with red cell production it was concluded that the increased cardiac output in dilution anemia compensates for the reduction in the oxygen content of each unit of arterial blood. Consequently, the stimulus to erythropoietic function must depend on the tissue tension of oxygen rather than on the oxygen content of arterial blood. Submitted on October 11, 1954 Accepted on December 4, 1954 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: P. WAYS, J. W. HUFF, C. H. KOSMALER, and L. E. YOUNG Polycythemia and Histologically Proven Renal Disease Arch Intern Med, February 1, 1961; 107(2): 154 - 162. [Abstract] [PDF]

	Copyright © 1955 by American Society of Hematology         Online ISSN: 1528-0020